Muriel Amblard is a CNRS Research Director at the « Institut of Biomolecules Max Mousseron » (IBMM) in Montpellier. After completing her PhD in Organic Chemistry at the University of Montpellier in the Lab of Prof Jean Martinez, she joined the group of Dr Paul Anderson at Merck Sharp & Dohm in USA as a postdoctoral fellow. In 1996, she received a CNRS position at the Laboratory of Amino Acids, Peptides and Proteins in Montpellier and became a team leader at the IBMM in 2007. Her research interests are mainly at the interface of chemistry, biology and structural analysis for developing bioactive compounds and chemical tools that can mimic biological systems. Muriel developed a number of potent receptor agonists and antagonists of several peptide hormones. Her recent work focuses on the design and synthesis of 1) predictable and stable ribbon and helical molecular architectures, 2) stapled peptides that are applied to the identification of cell penetrating compounds, and 3) inhibitors of protein/protein interactions. Another part of her research interest is devoted to the development of selective protein degraders by using Proteolysis-Targeting Chimeras (PROTACs) technology.