Photo de MARRA Alberto
MARRA Alberto      
Fonction : PR1
Thème de Recherche: Synthèse Glycosidique et Reconnaissance Moléculaire
Bureau: 0, Etg: 4, Bât: recherche - Site : ENSCM rue école normale

Activités de Recherche:     
Alberto Marra graduated summa cum laude in Pharmaceutical Sciences from the University of Pisa (Italy) in 1985. Then he moved to France and obtained his PhD in Organic Chemistry from the University Pierre et Marie Curie (Paris VI) in 1989 working in the laboratories of the Ecole Normale Supérieure under the supervision of Prof. P. Sinaÿ. He spent one more year in Paris as Researcher of the French National Research Council (CNRS). He was postdoctoral Research Associate at the University of Zurich (Switzerland) with Prof. A. Vasella (1991) and then moved to the University of Ferrara (Italy) where he joined the group of Prof. A. Dondoni.
He was appointed to a lectureship in Organic Chemistry at the Faculty of Engineering from 1992 to 1998 and was promoted to the position of Associate Professor in 1998 at the same University. Since 2002 he was teaching at the Faculty of Sciences of the University of Ferrara (Organic Chemistry, Natural Products Chemistry, Medicinal Chemistry). He was member of the Interdisciplinary Center for the Study of Inflammation of the University of Ferrara. He spent one month (June 2008) at the Université de Picardie Jules Verne (Amiens, France) and one month (June 2010) at the Université de Cergy-Pontoise (France) as Visiting Professor. On September 2012 he got a permanent position as Professor at the Université Montpellier 2 (France).
His research interest centres on carbohydrate chemistry. In particular he synthesized oligosaccharide fragments of blood group determinants, heparin, dermatan sulfate and developed new glycosyl donors and glycosylation promoters. Then he developed new synthetic methodologies for the preparation of C-oligosaccharides, C-glycosyl amino acids, and C-glycosyl phosphonates. Recent work is dealing with the synthesis and molecular recognition properties of glycosylated crown ethers, glycoside clusters, glycodendrimers, monomeric and polymeric calixarene derivatives.
Publications :
Domaines de Recherche:
  • Chimie
  • Sciences de l'ingénieur
Productions scientifiques :
+ Thiol-ene and thiol-yne-based synthesis of glycodendrimers as nanomolar inhibitors of wheat germ agglutinin doi link

Auteur(s): Ghirardello Mattia, Öberg Kim, Staderini S., Renaudet Olivier, Berthet Nathalie, Dumy P., Hed Yvonne, Marra A., Malkoch Michael, Dondoni Alessandro

(Article) Publié: Journal Of Polymer Science Part A Polymer Chemistry / Journal Of Polymer Science Part A-Polymer Chemistry, vol. 52 p.2422 - 2433 (2014)

+ Oxime Ligation: A Chemoselective Click-Type Reaction for Accessing Multifunctional Biomolecular Constructs doi link

Auteur(s): Ulrich S., Boturyn Didier, Marra A., Renaudet Olivier, Dumy P.

(Article) Publié: Chemistry - A European Journal, vol. 20 p.34 - 41 (2014)

+ Thiyl Glycosylation of Propargylated Octasilsesquioxane: Synthesis and Lectin-Binding Properties of Densely Glycosylated Clusters on a Cubic Platform doi link

Auteur(s): Marra A., Staderini S., Berthet Nathalie, Dumy P., Renaudet Olivier, Dondoni Alessandro

(Article) Publié: European Journal Of Organic Chemistry, vol. 2013 p.1144 - 1149 (2013)

+ Glycoside and peptide clustering around the octasilsesquioxane scaffold via photoinduced free-radical thiol–ene coupling. The observation of a striking glycoside cluster effect doi link

Auteur(s): Lo Conte Mauro, Staderini S., Chambery Angela, Berthet Nathalie, Dumy P., Renaudet Olivier, Marra A., Dondoni Alessandro

(Article) Publié: Organic & Biomolecular Chemistry / Organic And Biomolecular Chemistry, vol. 10 p. (2012)

+ Design of triazole-tethered glycoclusters exhibiting three different spatial arrangements and comparative study of their affinities towards PA-IL and RCA 120 by using a DNA-based glycoarray. hal link

Auteur(s): Moni Lisa, Pourceau G., Zang Jing, Meyer A., Vidal Sébastien, Souteyrand Eliane, Dondoni Alessandro, Morvan F., Chevolot Yann, Vasseur J.-J., Marra A.

(Article) Publié: Chembiochem, vol. 10 p.1369-1378 (2009)