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Effects of benzyl alcohol on transferrin and low density lipoprotein receptor mediated endocytosis in leukemic guinea pig B lymphocytes.
Auteur(s): Sainte-Marie Jacques, Vignes M., Vidal M., Philippot J. R., Bienvenüe A.
(Article) Publié:
Febs Letters, vol. 262 p.13-6 (1990)
Ref HAL: hal-00659475_v1
PMID 2318305
Résumé: We demonstrated that benzyl alcohol, a neutral local anesthetic drug, inhibits the uptake and degradation of lowdensity lipoprotein and endocytosis of transferrin receptors of guinea pig leukemic B lymphocytes (L2C). This inhibition is very rapid, concentration dependant and reversible by simple washing. Membrane fluidity of the living cells is also modified.
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