|Venomics in medicinal chemistry. |
Auteur(s): Dutertre S.
(Article) Publié: Future Medicinal Chemistry, vol. 6 p.1609-1610 (2014)
Ref HAL: hal-01089730_v1
Venom peptides mainly target ion channels, but also GPCRs, transporters and enzymes with high affinity and exquisite selectivity. The intermediate size of these peptidic toxins and their proteinaceous nature make them particularly suited formedicinal chemistry.