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C-O Ring Construction: The Oger/Lee/Galano Synthesis of 7(RS)-ST-Δ8-11-dihomo-Isofuran

by Bultel Valérie - published on

La chimie de l’équipe Synthèse de Lipides Bioactifs de l’IBMM est mise en lumière par Douglas Taber dans organic chemistry highlights.

The neurofurans and dihomoisofurans, exemplified by 7(RS)-ST-Δ8-dihomo-IsoF (29), are potential biomarkers of oxidative stress. Camille Oger and Jean-Marie Galano of Université de Montpellier and Jetty Chung-Yung Lee of the University of Hong Kong described (Chem. Eur. J. 2015, 21, 2442. DOI: 10.1002/chem.201405497) a general route to the isofurans and neurofurans, based on the Borhan cyclization of 27 to 28.


Monday, November 9, 2015
Douglass F. Taber University of Delaware

View online : http://www.organic-chemistry.org/Hi...