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Séminaire Chimie ED459

Nanomedicine: What is happening and where is this field going in the next decade?

Prof. André Nel (Prof. of Medicine, Chief of NanoMedicine Division, Director of UC CEIN, David Geffen School of Medicine, UCLA, Los Angeles, USA)

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Le Jeudi 14 Juin 2012 à 14h
CNRS, Amphithéâtre de la Délégation Régionale LR (1919 rte de Mende, Montpellier)
(2e conférence)

Over the past decade, nanomedicine and nanobiology has undergone a dramatic transformation from fantasy to real science. The days of discussing advances in the context of “nanobots” are over, and the systems and nanomaterials that have emerged provide major analytical, therapeutic and diagnostic advantages over conventional molecule-based structures and approaches. We have come to recognize that much of biology is executed at the nanoscale level, therefore providing a rational approach to using discovery about the structure and function of engineered nanomaterials at the nano-bio interface for interrogation of disease, diagnosis, treatment, and imaging at levels of sophistication not possible before. Fabrication of a host of nanostructures has been coupled with advanced chemical manipulation to impart biological recognition and interaction capabilities. Early work has provided significant evidence that the properties afforded by nanostructures offer not only different but also better ways of detecting, managing, treating, and preventing disease. Analytical tools have been invented that allow imaging and manipulation of biological structures that can revolutionize the fields of medicine and biology. These tools are dramatically accelerating the fundamental understanding of complex biological systems and providing a basis for understanding the rapid translational advances being made on the nanomedicine front. Through the application of nanomaterials to impact in vitro and in vivo biological systems, and with sophisticated tools to monitor such nano-bio interactions, it has become increasingly appreciated that such interactions are complex and warrant directed evaluation as we move forward in the next ten years. I will review representative examples of nanotechnology-based tools, materials, and systems that are having major impacts in biology and medicine, including our multi-functional mesoporous silica nanoparticle treatment platform. I will review the major advances that we expect in for nano medicine globally based on the recent series of international workshops and vision we have developed for the US government in the next decade.

N.B. Prof. André Nel will give another lecture the same day at 10:30 a.m. (same place).

Contact local ICGM : Jean-Olivier Durand

Abstracts of 2 Lectures + CV A. Nel (PDF)


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