Author Archive for: cclavel

Entries by Caroline Clavel

New article in Simon Galas’ group : Influence of Oleacein, an Olive Oil and Olive Mill Wastewater Phenolic Compound, on Caenorhabditis elegans Longevity and Stress Resistance.

Oleacein, a bioactive compound of olive oil and olive mill wastewater, has one of the strongest antioxidant activities among olive phenolics. However, few reports explore the in vivo antioxidant activity of oleacein, with no clear identification of the biological pathway involved. Earlier studies have demonstrated a link between stress resistance, such as oxidative stress, and […]

PhD proposal – GREEN CHEMISTRY AND ENABLING TECHNOLOGIES team

Mechano-Activation of Molecular Nitrogen for Ammonia Synthesis   Ammonia (NH3) is the second most mass-produced molecule (180 MT/year) and a major intermediate for the production of chemicals and fertilizers. There is also an increasing interest on ammonia as a carbon-free fuel, and even as a hydrogen vector due to its physical properties. Despite its many […]

A publication by the IBMM Green Chemistry team together with PolyPeptide Group and the IBMM peptide team made it to the cover of the journal ChemistryEurope from Wiley Chemistry Europe.

  This work is dedicated to Prof. Jean Martinez, at the occasion of his 75th birthday, a strong supporter and active collaborator of the IBMM GreenChem team. We reported in this publication how applications of screw-generated mechanical forces to a mixture of amino acids and coupling agents, delivered to the top of a TSE barrel […]

A new publication by team GreenChem highlighted by ChemistryViews

The team Green Chemistry and Enabling Technologies published new results on the mechanochemical synthesis of NO-releasing drugs. These drugs belong to the family of iminosydnones and their biological activity arises from the release of NO. This high reactivity can make their synthesis and isolation very challenging. And mechanochemistry comes to the rescue with facilitated solvent-free […]

The team of Muriel Amblard and Anthony Martin publishes in Nature Cancer!

PROTACs-PI3Kγ open a new pathway for targeted treatment of acute myeloid leukemia (AML) Acute myeloid leukemia (AML) is the most common leukemia in adults. Recent medical advances have achieved up to 50% 5-year survival rates. However, this rate still needs improvement, especially for individuals aged 60 and over, whose 5-year survival rate is only 10%, […]

IBMM welcomes Prof Sébastien Papot, on June 26th

Wednesday June 26Th at 10 am Prof. Sébastien Papot will give a seminar entitled « Comprendre et manipuler les processus biologiques grâce à la formation et/ou la rupture contrôlée de liaisons chimiques » – IBMM, Amphithéâtre Balard Sébastien Papot is professor at Poitiers University and the head of the “organic synthesis” team at the IC2MP. He is […]

News about tardigrades!

41% of tardigrade genes do not exist in any other living species, and some of them have exceptional properties for combating extreme stress (temperature, pressure, absolute zero, outer space, etc.). Professor Simon Galas’s team has just published an article in the American journal PLOS ONE, revealing for the first time the different strategies used by […]

PhD proposal – ANALYTIC SCIENCES of BIOMOLECULES team

THERAPEUTIC PEPTIDES AND THE CONTROL OF THEIR CHIRALITY : MAJOR CHALLENGE IN ANALYTICAL SCIENCES This thesis is part of a large-scale research project aiming at probing the chirality of therapeutic peptides. This project is bringing together the vast majority of the IBMM analytical team (5 teacher-researchers, 3 technical staff). Preliminary work was carried out as […]

“Polymers for Health” team welcomes Emmanuel Pauthe and organizes a conference

Emmanuel Pauthe, 52 years-old, Professor at CY Cergy-Paris Université, director of ERRMECe Laboratory and responsible of the Master of Science and Engineering in Biomaterial for Health. Emmanuel Pauthe obtained his PhD in Biological Engineering in 1999 at the University of Technology of Compiegne. For 25 years he has conducted several funded projects mainly in Protein […]