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Entries by Caroline Clavel

BUT2-3/2A Internship: Investigation of Protein/Nanoparticle Release from Hybrid Silylated Hydrogels: Impact of Overall Charge (ADAPT Project)

Project Description Biopolymer-based hydrogels are promising matrices for the controlled delivery of therapeutic agents. The ADAPT project aims to develop a new generation of hydrogels formed through sol-gel crosslinking of silylated polysaccharides. The objective is to modulate electrostatic interactions between the hydrogel matrix and the encapsulated proteins or nanoparticles without relying on covalent bonds. This […]

M2/3A Internship: Multifunctional Degradable Polymers for Stimuli-Responsive Hydrogels: Controlled Drug Delivery and Shape-Morphing

Project Description Stimuli-responsive biomaterials, capable of modifying their properties (active compound release, shape changes) in response to non-invasive external stimuli (magnetic fields, infrared irradiation), are attracting increasing interest in regenerative medicine. Thanks to their multivalent architecture, star-shaped polymers offer opportunities to tailor the structure and properties of the resulting hydrogel networks. However, controlling both the […]

BUT2 Internship: Peptide and Organic Synthesis – Development of PROTAC Molecules for the Treatment of Parasitic Diseases

Project Description This internship is part of the ANR DIN-R research project, which aims to develop inhibitors of the DAF-12 nuclear receptor to treat parasitic diseases and combat nematode infections. Current treatments rely on anthelmintic drugs, whose effectiveness is increasingly compromised by the emergence of drug resistance, with no alternative expected in the short term. […]

M2/3A Internship: Development of a Hybrid, Degradable Dermal Substitute Loaded with Bioactive Compounds from Réunion Island Biodiversity

Project Description Founded in 2024 and based on Réunion Island, Skinegy initiated the Skincense research project, conducted in collaboration with the Polymers for Health and Biomaterials (PHBM) team at the Institut des Biomolécules Max Mousseron (IBMM). The project focuses on the development of a new therapeutic approach for the treatment of chronic wounds, including pressure […]

M2/3A Internship: Development of New Copolymers for 3D Printing of Tissue Regeneration Scaffolds

Keywords Lipids, polymers, photopolymerization, 3D printing, material processing and property characterization Project Description We have recently developed a new family of photosensitive copolymers based on vegetable oil and polylactic acid (PLA), referred to as H-PLA-MA. The presence of photosensitive functional groups in these materials opens up opportunities for their use in additive manufacturing by photopolymerization, […]

6 months intership : Role of the Ghrelin System in Weight Gain in Patients with Breast Cancer

Background Unlike many other types of cancer, which are often associated with weight loss, patients with breast cancer may experience weight gain following diagnosis. This phenomenon, which remains poorly understood, represents an important public health issue. It is associated with an increased risk of mortality, both through the risk of cancer recurrence and through the […]

6 months Internship: Controlled and targeted photothermal delivery of CDK4 inhibitors by Prussian Blue nanoparticles into cellular and ex ovo models of pancreatic cancer.

Pancreatic cancer (PC) has a less than 1% overall 10-year survival rate and is typically diagnosed at an advanced stage with limited treatment options. Surgical resection remains the only potentially curative treatment, generally followed by adjuvant chemotherapy. For non-resectable metastatic PC, current chemotherapy regimens provide limited benefit and are associated with significant toxicity. In addition, […]

JIREC 2026 featured in L’Actualité Chimique

The September issue of L’Actualité Chimique looks back on the great success of the 36th JIREC, held from 27 to 30 January in Sète around the theme “Chemistry, ecological transition and sustainable development”. The event brought together more than 150 participants from across France and Senegal for three days of conferences, workshops and discussions focusing […]

HyriaMed: a new start-up stemming from research by the PHBM team

Founded in July 2026, the start-up HyriaMed emerged from research carried out within the Polymers for Health and Biomaterials (PHBM) team at the Institut des Biomolécules Max Mousseron (IBMM). HyriaMed is developing PEASY, an innovative medical device for urine collection without skin adhesives, designed to improve the comfort and autonomy of men with urinary incontinence. […]

6 months interneship : Hybrid biomaterials for the treatment of prostate cancer by combination therapy

Keywords: Polymer chemistry, nanoparticles, hydrogels, drug delivery Project description A growing interest in nanoparticle-hydrogel hybrids and their applications for asset delivery is witnessed. Hydrogels are typically used to protect and modulate the release of nanoparticles while nanoparticles are used as cargo for active pharmaceutical ingredients (API). Despite the expected therapeutic benefits of combination therapies, little […]

 

Institut des Biomolécules Max Mousseron
UMR 5247
Pôle Chimie Balard Recherche
1919 route de Mende
34293 Montpellier