A new potent and stable DNA methyltransferase inhibitor developed by the Glycochemistry & Molecular Recognition team for cancer treatment
The researchers of the Glycochemistry & Molecular Recognition group of the IBMM have just published a paper on the Journal of Medicinal Chemistry, where they show the results of the rational optimisation of their flavanone derivatives as DNA methyltransferase (DNMT) inhibitors. Among the new synthesised compounds, they identified compound 34b, a novel dihalo-methoxyflavanone with high […]