Thérapies photodynamiques et photothermiques ciblant les anhydrases carboniques associées aux tumeurs : Synergie multimodale pour le traitement des tumeurs hypoxiques. Financement : Ligue Nationale contre le Cancer Equipe d’accueil : Institut des Biomolécules Max Mousseron, UMR 5247 Université de Montpellier, CNRS, ENSCM, Equipe : ChemBioNAC Contexte : L’utilisation combinée de la thérapie photothermique (PTT) et […]
Development of a new photocrosslinking chemistry for Bioprinting Period: 6 months from January/February to June/July 2025 Internship supervisor: Dr Cécile Echalier Contact: Research team: IBMM Peptides www.ibmmpeptide.com Internship location: IBMM, Pole Chimie Balard, 1919 Route de Mende, Montpellier, France. Summary This Master’s research project at the interface between organic chemistry, photochemistry, inorganic chemistry […]
Béatrice Roy (Nucleosides and Phosphorylated Effectors team) and Jean-Yves Winum (ChemBioNAC team), both professors at the Chemistry Department of the Faculty of Sciences, are co-authors with Stéphane Perrio (Professor, University of Caen) of the book “Structure of Organic Molecules” from the Petits Experts Sciences collection by DUNOD editions, published in August 2024. This pocket-sized manual, […]
A nomenclature update for isoprostanoids has just been proposed by Camille Oger and collaborators, and published in Progress Lipid Research. The entire SLB-IBMM team congratulates her and is delighted to see the very positive reception this article has received from the lipid scientific community.” https://doi.org/10.1016/j.plipres.2024.101301
In 2019, IUPAC recognized mechanochemistry as one of the 10 innovative technologies that would change the world. This technology, and more specifically ball milling, offers numerous benefits linked to environmentally-friendly chemistry (short reaction times, solvent-free reactions, different selectivity compared to solution…). Ball mills can be used in a wide range of applications, including materials chemistry […]
SYNTHESIS OF AFFINITY PROBES TO DECIPHER THE MODE OF ACTION OF ANS RECEPTOR ANTAGONIST Context and objective of the project In the context of liver cancer, despite existing treatment most patients remain at high risk due to resistance development to tyrosine kinase inhibitors (TKIs). It was discovered an indole-ethanamine compound, targeting ANS receptors, has synergistic […]
Oleacein, a bioactive compound of olive oil and olive mill wastewater, has one of the strongest antioxidant activities among olive phenolics. However, few reports explore the in vivo antioxidant activity of oleacein, with no clear identification of the biological pathway involved. Earlier studies have demonstrated a link between stress resistance, such as oxidative stress, and […]
Mechano-Activation of Molecular Nitrogen for Ammonia Synthesis Ammonia (NH3) is the second most mass-produced molecule (180 MT/year) and a major intermediate for the production of chemicals and fertilizers. There is also an increasing interest on ammonia as a carbon-free fuel, and even as a hydrogen vector due to its physical properties. Despite its many […]
This work is dedicated to Prof. Jean Martinez, at the occasion of his 75th birthday, a strong supporter and active collaborator of the IBMM GreenChem team. We reported in this publication how applications of screw-generated mechanical forces to a mixture of amino acids and coupling agents, delivered to the top of a TSE barrel […]
The team Green Chemistry and Enabling Technologies published new results on the mechanochemical synthesis of NO-releasing drugs. These drugs belong to the family of iminosydnones and their biological activity arises from the release of NO. This high reactivity can make their synthesis and isolation very challenging. And mechanochemistry comes to the rescue with facilitated solvent-free […]
Institut des Biomolécules Max Mousseron
UMR 5247
Pôle Chimie Balard Recherche
1919 route de Mende
34293 Montpellier