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LISTE DES PUBLICATIONS
de
L’équipe « OLIGONUCLEOTIDES MODIFIES »
(IBMM, UMR 5247 CNRS-UM-ENSCM)
2006 - janvier 2018

a) Publications (journaux à comité de lecture)

2018

137) Amirbekyan, K. ; Mansot, J. ; Ohara, K. ; Markarian, S. A. ; Vasseur, J.-J. ; Smietana, M. Template-directed excimer formation via specific non-covalent interactions between pyrene guanidinium derivatives and nucleic acids. Tetrahedron Letters 2018, 59 (3), 295-298

2017

136) Meyer, A. ; Vasseur, J.-J. ; Dumy, P. ; Morvan, F. Phthalimide-oxy derivatives for 3’- or 5’-Conjugation of Oligonucleotides by Oxime Ligation and Circularization of DNAs by « Bis- or Tris-Click » Oxime Ligation. European Journal of Organic Chemistry 2017, (46), 6931-6941

135) Angeli, A. ; Dupin, L. ; Madaoui, M. ; Li, M. ; Vergoten, G. ; Wang, S. ; Meyer, A. ; Géhin, T. ; Vidal, S. ; Vasseur, J.-J., et al. Glycoclusters with Additional Functionalities for Binding to the LecA Lectin from Pseudomonas aeruginosa. ChemistrySelect 2017, 2 (32), 10420-10427

134) Riccardi, C. ; Russo Krauss, I. ; Musumeci, D. ; Morvan, F. ; Meyer, A. ; Vasseur, J.-J. ; Paduano, L. ; Montesarchio, D. Fluorescent Thrombin Binding Aptamer-Tagged Nanoparticles for an Efficient and Reversible Control of Thrombin Activity. ACS Applied Materials & Interfaces 2017, 9 (41), 35574-35587

133) Reverte, M. ; Barvik, I. ; Vasseur, J. J. ; Smietana, M., RNA-directed off/on switch of RNase H activity using boronic ester formation. Organic & Biomolecular Chemistry 2017, 15 (38), 8204-8210

132) Duchemin, N. ; Heath-Apostolopoulos, I. ; Smietana, M. ; Arseniyadis, S., A decade of DNA-hybrid catalysis : from innovation to comprehension. Organic & Biomolecular Chemistry 2017, 15 (34), 7072-7087.

131) Aouadi, W. ; Eydoux, C. ; Coutard, B. ; Martin, B. ; Debart, F. ; Vasseur, J. J. ; Contreras, J. M. ; Morice, C. ; Querat, G. ; Jung, M. L. ; Canard, B. ; Guillemot, J. C. ; Decroly, E., Toward the identification of viral cap-methyltransferase inhibitors by fluorescence screening assay. Antiviral Research 2017, 144, 330-339.

130) Angeli, A. ; Li, M. C. ; Dupin, L. ; Vergoten, G. ; Noel, M. ; Madaoui, M. ; Wang, S. ; Meyer, A. ; Gehin, T. ; Vidal, S. ; Vasseur, J. J. ; Chevolot, Y. ; Morvan, F., Design and Synthesis of Galactosylated Bifurcated Ligands with Nanomolar Affinity for Lectin LecA from Pseudomonas aeruginosa. Chembiochem 2017, 18 (11), 1036-1047.

129) Barbeyron, R. ; Vasseur, J.-J. ; Baraguey, C. ; Smietana, M., Synthesis of 3′-deoxy-3′-iminodiacetic acid and 3′-deoxy-3′-aminodiethanol thymidine analogues and NMR study of their complexation with boronic acids. Tetrahedron 2017, 73 (17), 2468-2475.

128) Ovadia, R. ; Mondielli, C. ; Vasseur, J. J. ; Baraguey, C. ; Alvarez, K., Contribution to PNA-RNA Chimera Synthesis : One-Pot Microwave-Assisted Ugi Reaction to Obtain Dimeric Building Blocks. European Journal of Organic Chemistry 2017, 2017 (3), 469-475.

127) Tamarkin-Ben-Harush, A. ; Vasseur, J. J. ; Debart, F. ; Ulitsky, I. ; Dikstein, R., Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress. Elife 2017, 6, e21907.

126) Bañuls, M.-J. ; Jiménez-Meneses, P. ; Meyer, A. ; Vasseur, J.-J. ; Morvan, F. ; Escorihuela, J. ; Puchades, R. ; Maquieira, Á., Improved Performance of DNA Microarray Multiplex Hybridization Using Probes Anchored at Several Points by Thiol–Ene or Thiol–Yne Coupling Chemistry. Bioconjugate Chemistry 2017, 28 (2), 496-506.

125) Aouadi, W. ; Blanjoie, A. ; Vasseur, J.-J. ; Debart,F. ; Canard, B. ; Decroly, E. Binding of the methyl donor SAM to MERS-CoV 2’ -O-methyltransferase nsp16 promotes the recruitment of the allosteric activator nsp10. Journal of Virology 2017, 91 (5), e2217-16.

124) Coutard, B. ; Barral, K. ; Lichiere, J. ; Selisko, B. ; Martin, B. ; Aouadi, W. ; Ortiz-Lombardia, M. ; Debart,F. ; Vasseur, J.-J. ; Guillemot, J.-C. ; Canard, B. ; Decroly, E. The Zika virus methyltransferase : structure and functions for drug design perspectives. Journal of Virology 2017, 91 (5), e2202-16.

123) Mauer, J. ; Luo, X. B. ; Blanjoie, A. ; Jiao, X. F. ; Grozhik, A. V. ; Patil, D. P. ; Linder, B. ; Pickering, B. F. ; Vasseur, J. J. ; Chen, Q. Y. ; Gross, S. S. ; Elemento, O. ; Debart, F. ; Kiledjian, M. ; Jaffrey, S. R., Reversible methylation of m(6)A(m) in the 5 ’ cap controls mRNA stability. Nature 2017, 541 (7637), 371-375.

2016

122) Thangaraj, V. ; Lepoitevin, M. ; Smietana, M., Balanzat, E. ; Bechelany, M. ; Janot, J.-M. ; Vasseur, J.-J. ; Subramanian, S. ; Balme, S. Detection of short ssDNA and dsDNA by current-voltage measurements using conical nanopores coated with Al2O3 by atomic layer deposition. Microchimica Acta 2016, 183 (3), 1011-1017.

121) Reverte, M. ; Vaissiere, A. ; Boisguerin, P. ; Vasseur, J.-J. ; Smietana, M. RNase H-Assisted Imaging of Peroxynitrite in Living Cells with 5′-Boronic Acid Modified DNA. ACS Sensors 2016, 1 (8), 970-974.

120) Wang, S. ; Dupin, L. ; Noel, M. ; Carroux, C. J. ; Renaud, L. ; Gehin, T. ; Meyer, A. ; Souteyrand, E. ; Vasseur, J. J. ; Vergoten, G. ; Chevolot, Y. ; Morvan, F.. Toward the Rational Design of Galactosylated Glycoclusters That Target Pseudomonas aeruginosa Lectin A (LecA) : Influence of Linker Arms That Lead to Low-Nanomolar Multivalent Ligands. Chemistry-a European Journal 2016, 22 (33), 11785-11794.

119) Brundu, S. ; Palma, L. ; Picceri, G. G. ; Ligi, D. ; Orlandi, C. ; Galluzzi, L. ; Chiarantini, L. ; Casabianca, A. ; Schiavano, G. F. ; Santi, M. ; Mannello, F. ; Green, K. ; Smietana, M. ; Magnani, M. ; Fraternale, A. Glutathione Depletion Is Linked with Th2 Polarization in Mice with a Retrovirus-Induced Immunodeficiency Syndrome, Murine AIDS : Role of Proglutathione Molecules as Immunotherapeutics. Journal of Virology 2016, 90 (16), 7118-7130.

118) Biscans, A. ; Rouanet, S. ; Vasseur, J.-J. ; Dupouy, C. ; Debart, F. A versatile post-synthetic method on a solid support for the synthesis of RNA containing reduction-responsive modifications. Organic & Biomolecular Chemistry 2016, 14 (29), 7010-7017.

117) Duchemin, N. ; Benedetti, E. ; Bethge, L. ; Vonhoff, S. ; Klussmann, S. ; Vasseur, J.-J. ; Cossy, J. ; Smietana, M. ; Arseniyadis, S. ; , Expanding biohybrid asymmetric catalysis into the realm of RNA. Chemical Communications 2016, 52 (55), 8604-8607.

116) Amirbekyan, K. ; Duchemin, N. ; Benedetti, E. ; Joseph, R. ; Colon, A. ; Markarian, S. A. ; Bethge, L. ; Vonhoff, S. ; Klussmann, S. ; Cossy, J. ; Vasseur, J.-J. ; Arseniyadis, S. ; Smietana, M., Design, Synthesis, and Binding Affinity Evaluation of Hoechst 33258 Derivatives for the Development of Sequence-Specific DNA-Based Asymmetric Catalysts. ACS Catalysis 2016, 6, 3096-3105.

115) Thangaraj, V. ; Lepoitevin, M. ; Smietana, M. ; Balanzat, E. ; Bechelany, M. ; Janot, J.-M. ; Vasseur, J.-J. ; Subramanian, S. ; Balme, S., Detection of short ssDNA and dsDNA by current-voltage measurements using conical nanopores coated with Al2O3 by atomic layer deposition. Microchimica Acta 2016, 183 (3), 1011-1017.

2015

114) Barbeyron, R. ; Martin, A. R. ; Vasseur, J.-J. ; Smietana, M. DNA-templated borononucleic acid self assembly : a study of minimal complexity. RSC Advances 2015, 5 (128), 105587-105591.

113) Ligeour, C. ; Dupin, L. ; Angeli, A. ; Vergoten, G. ; Vidal, S. ; Meyer, A. ; Souteyrand, E. ; Vasseur, J.-J. ; Chevolot, Y. ; Morvan, F. Importance of topology for glycocluster binding to Pseudomonas aeruginosa and Burkholderia ambifaria bacterial lectins. Organic & Biomolecular Chemistry 2015, 13 (46), 11244-11254.

112) Paesen, G. C. ; Collet, A. ; Sallamand, C. ; Debart, F. ; Vasseur, J.-J. ; Canard, B. ; Decroly, E. ; Grimes, J. M. X-ray structure and activities of an essential Mononegavirales L-protein domain. Nat Commun 2015, 6, N° 8749, DOI : 10.1038/ncomms9749.

111) Ovadia, R. ; Lebrun, A. ; Barvik, I. ; Vasseur, J.-J. ; Baraguey, C. ; Alvarez, K. Synthesis and structural characterization of monomeric and dimeric peptide nucleic acids prepared by using microwave-promoted multicomponent reactions. Organic & Biomolecular Chemistry 2015, 13 (45), 11052-11071.

110) Reverte, M. ; Vasseur, J.-J. ; Smietana, M. Nuclease stability of boron-modified nucleic acids : application to label-free mismatch detection. Organic & Biomolecular Chemistry 2015, 13 (43), 10604-10608.

109) Dupin, L. ; Zuttion, F. ; Géhin, T. ; Meyer, A. ; Phaner-Goutorbe, M. ; Vasseur, J.-J. ; Souteyrand, E. ; Morvan, F. ; Chevolot, Y. Effects of the Surface Densities of Glycoclusters on the Determination of Their IC50 and Kd Value Determination by Using a Microarray. ChemBioChem 2015, 16 (16), 2329-2336.

108) Biscans, A. ; Rouanet, S. ; Bertrand, J.-R. ; Vasseur, J.-J. ; Dupouy, C. ; Debart, F. Synthesis, binding, nuclease resistance and cellular uptake properties of 2′-O-acetalester-modified oligonucleotides containing cationic groups. Bioorganic & Medicinal Chemistry 2015, 23 (17), 5360-5368.

107) Ligeour, C. ; Vidal, O. ; Dupin, L. ; Casoni, F. ; Gillon, E. ; Meyer, A. ; Vidal, S. ; Vergoten, G. ; Lacroix, J.-M. ; Souteyrand, E. ; Imberty, A. ; Vasseur, J.-J. ; Chevolot, Y. ; Morvan, F. Mannose-centered aromatic galactoclusters inhibit the biofilm formation of Pseudomonas aeruginosa. Organic & Biomolecular Chemistry 2015, 13 (31), 8433-8444.

106) Li, C. ; Guillen, J. ; Rabah, N. ; Blanjoie, A. ; Debart, F. ; Vasseur, J.-J. ; Canard, B. ; Decroly, E. ; Coutard, B. mRNA Capping by Venezuelan Equine Encephalitis Virus nsP1 : Functional Characterization and Implications for Antiviral Research. Journal of Virology 2015, 89 (16), 8292-8303.

105) Priet, S. ; Lartigue, A. ; Debart, F. ; Claverie, J.-M. ; Abergel, C., mRNA maturation in giant viruses : variation on a theme. Nucleic Acids Research 2015, 43 (7), 3776-3788.

104) Meyer, A. ; Noel, M. ; Vasseur, J.-J. ; Morvan, F., Hetero-Click Conjugation of Oligonucleotides with Glycosides Using Bifunctional Phosphoramidites. European Journal of Organic Chemistry 2015, (13), 2921-2927.

103) Astalayo-Adrian, S. ; Lartia, R. ; Meyer, A. ; Vasseur, J.-J. ; Morvan, F. ; Defrancq, E., Assessment of the Full Compatibility of Copper(I)-Catalyzed Alkyne-Azide Cycloaddition and Oxime Click Reactions for bis-Labelling of Oligonucleotides. ChemistryOpen 2015, 4 (22), 169-173.

102) Benedetti, E. ; Duchemin, N. ; Bethge, L. ; Vonhoff, S. ; Klussmann, S. ; Vasseur, J.-J. ; Cossi, J. ; Smietana, M. ; Arseniyadis, S., DNA-cellulose, an economical, fully recyclable and highly effective chiral biomaterial for asymmetric catalysis. Chemical Communication 2015, 51 (28), 6076-6079.

101) Thillier, Y. ; Sallamand, C. ; Baraguey, C. ; Vasseur, J.-J. ; Debart, F., Solid-Phase Synthesis of Oligonucleotide 5′-(α-P-Thio)triphosphates and 5′-(α-P-Thio)(β,γ-methylene)triphosphates. European Journal of Organic Chemistry 2015, (2), 302-308.

100) Barbeyron, R. ; Vasseur, J.-J. ; Smietana, M., pH-controlled DNA- and RNA-templated assembly of short oligomers. Chemical-Science 2015, 6 (1), 542-547.

2014

99) Biscans, A. ; Bos, M. ; Martin, A.R. ; Ader, N. ; Sczakiel, G. ; Vasseur, J.-J. ; Dupouy, C. ; Debart, F., Direct Synthesis of Partially Modified 2′-O-Pivaloyloxymethyl RNAs by a Base-Labile Protecting Group Strategy and their Potential for Prodrug-Based Gene-Silencing Applications. Chembiochem 2014, 15 (18), 2674-2679.

98) Ligeour, C. ; Dupin, L. ; Marra, A. ; Vergoten, G. ; Meyer, A. ; Dondoni, A. ; Souteyrand, E. ; Vasseur, J.-J. ; Chevolot, Y. ; Morvan, F., Synthesis of Galactoclusters by Metal-Free Thiol “Click Chemistry” and Their Binding Affinities for Pseudomonas aeruginosa Lectin LecA. European Journal of Organic Chemistry 2014, 2014 (34), 7621-7630.

97) Casoni, F. ; Dupin, L. ; Vergoten, G. ; Meyer, A. ; Ligeour, C. ; Gehin, T. ; Vidal, O. ; Souteyrand, E. ; Vasseur, J.-J. ; Chevolot, Y. ; Morvan, F., The influence of the aromatic aglycon of galactoclusters on the binding of LecA : a case study with O-phenyl, S-phenyl, O-benzyl, S-benzyl, O-biphenyl and O-naphthyl aglycons. Organic & Biomolecular Chemistry 2014, 12 (45), 9166-9179.

96) Barbeyron, R. ; Benedetti, E. ; Cossy, J. ; Vasseur, J.-J. ; Arseniyadis, S. ; Smietana, M., Recent Developments in Alkyne Borylations. Tetrahedron 2014, 70 (45), 8431-8452.

95) Chevolot, Y. ; Laurenceau, E. ; Phaner-Goutorbe, M. ; Monnier, V. ; Souteyrand, E. ; Meyer, A. ; Géhin, T. ; Vasseur, J.-J. ; Morvan, F., DNA directed immobilization glycocluster array : applications and perspectives. Current Opinion in Chemical Biology 2014, 18 (0), 46-54.

94) Bolognesi, M. L. ; Bergamini, C. ; Fato, R. ; Oiry, J. ; Vasseur, J.-J. ; Smietana, M., Synthesis of new lipoic Acid conjugates and evaluation of their free radical scavenging and neuroprotective activities. Chemical biology & drug design 2014, 83 (6), 688-96.

93) Gerland, B. ; Goudot, A. ; Ligeour, C. ; Pourceau, G. ; Meyer, A. ; Vidal, S. ; Gehin, T. ; Vidal, O. ; Souteyrand, E. ; Vasseur, J.-J. ; Chevolot, Y. ; Morvan, F., Structure Binding Relationship of Galactosylated Glycoclusters toward Pseudomonas aeruginosa Lectin LecA Using a DNA-Based Carbohydrate Microarray. Bioconjugate Chemistry 2014, 25 (2), 379-392.

92) Elayadi, H. ; Smietana, M. ; Vasseur, J. J. ; Balzarini, J. ; Lazrek, H. B., Synthesis of 1,2,3-triazolyl nucleoside analogs as potential anti-influenza A (H3N2 subtype) virus agents. Archiv der Pharmazie 2014, 347 (2), 134-41.

91) Escande, V. ; Garoux, L. ; Grison, C. ; Thillier, Y. ; Debart, F. ; Vasseur, J.-J. ; Boulanger, C. ; Grison, C., Ecological catalysis and phytoextraction : Symbiosis for future. Applied Catalysis B : Environmental 2014, 146 (0), 279-288.

2013

90) De Tito, S. ; Morvan, F. ; Meyer, A. ; Vasseur, J.-J. ; Cummaro, A. ; Petraccone, L. ; Pagano, B. ; Novellino, E. ; Randazzo, A. ; Giancola, C. ; Montesarchio, D., Fluorescence Enhancement upon G-Quadruplex Folding : Synthesis, Structure, and Biophysical Characterization of a Dansyl/Cyclodextrin-Tagged Thrombin Binding Aptamer. Bioconjugate Chemistry 2013, 24 (11), 1917-1927.

89) Wang, J. ; Benedetti, E. ; Bethge, L. ; Vonhoff, S. ; Klussmann, S. ; Vasseur, J.-J. ; Cossy, J. ; Smietana, M. ; Arseniyadis, S., DNA vs. Mirror-Image DNA : A Universal Approach to Tune the Absolute Configuration in DNA-Based Asymmetric Catalysis. Angewandte Chemie International Edition 2013, 52 (44), 11546-11549.

88) Ligeour, C. ; Audfray, A. ; Gillon, E. ; Meyer, A. ; Galanos, N. ; Vidal, S. ; Vasseur, J.-J. ; Imberty, A. ; Morvan, F., Synthesis of branched-phosphodiester and mannose-centered fucosylated glycoclusters and their binding studies with Burkholderia ambifaria lectin (BambL). RSC Advances 2013, 3 (42), 19515-19524.

87) Lereau, M. ; Fournier-Wirth, C. ; Mayen, J. ; Farre, C. ; Meyer, A. ; Dugas, V. ; Cantaloube, J.-F. ; Chaix, C. ; Vasseur, J.-J. ; Morvan, F., Development of Innovative and Versatile Polythiol Probes for Use on ELOSA or Electrochemical Biosensors : Application in Hepatitis C Virus Genotyping. Analytical Chemistry 2013, 85 (19), 9204-9212.

86) Thillier, Y. ; Stevens, S. K. ; Moy, C. ; Taylor, J. ; Vasseur, J.-J. ; Beigelman, L. ; Debart, F., Solid-phase synthesis of 5′-triphosphate 2′-5′-oligoadenylates analogs with 3′-O-biolabile groups and their evaluation as RNase L activators and antiviral drugs. Bioorganic & Medicinal Chemistry 2013, 21 (17), 5461-5469.

85) Barral, K. ; Sallamand, C. ; Petzold, C. ; Coutard, B. ; Collet, A. ; Thillier, Y. ; Zimmermann, J. ; Vasseur, J. J. ; Canard, B. ; Rohayem, J. ; Debart, F. ; Decroly, E., Development of specific dengue virus 2′-O- and N7-methyltransferase assays for antiviral drug screening. Antiviral Research 2013, 99 (3), 292-300.

84) Piton, J. ; Larue, V. ; Thillier, Y. ; Dorleans, A. ; Pellegrini, O. ; de la Sierra-Gallay, I. L. ; Vasseur, J.-J. ; Debart, F. ; Tisne, C. ; Condon, C., Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates. Proceedings of the National Academy of Sciences of the United States of America 2013, 110 (22), 8858-8863.

83) Barbeyron, R. ; Wengel, J. ; Vasseur, J.-J. ; Smietana, M., Boronic acid-based autoligation of nucleic acids : influence of the nature of the 3 ’-end ribonucleotidic strand. Monatshefte Fur Chemie 2013, 144 (4), 495-500.

82) Fraternale, A. ; Crinelli, R. ; Casabianca, A. ; Paoletti, M. F. ; Orlandi, C. ; Carloni, E. ; Smietana, M. ; Palamara, A. T. ; Magnani, M., Molecules Altering the Intracellular Thiol Content Modulate NF-kB and STAT-1/IRF-1 Signalling Pathways and IL-12 p40 and IL-27 p28 Production in Murine Macrophages. Plos One 2013, 8 (3), e57866.

81) Martin, A. R. ; Vasseur, J.-J. ; Smietana, M., Boron and nucleic acid chemistries : merging the best of both worlds. Chemical Society Reviews 2013, 42 (13), 5684-5713.

80) Spinelli, N. ; Defrancq, E. ; Morvan, F., Glycoclusters on oligonucleotide and PNA scaffolds : synthesis and applications. Chemical Society Reviews 2013, 42 (11), 4557-4573.

79) Thillier, Y. ; Losfeld, G. ; Escande, V. ; Dupouy, C. ; Vasseur, J.-J. ; Debart, F. ; Grison, C., Metallophyte wastes and polymetallic catalysis : a promising combination in green chemistry. The illustrative synthesis of 5’-capped RNA. RSC Advances 2013, 3 (15), 5204-5212.

78) Baraguey, C. ; Lescrinier, E. ; Lavergne, T. ; Debart, F. ; Herdewijn, P. ; Vasseur, J.-J., The biolabile 2’-O-pivaloyloxymethyl modification in an RNA helix : an NMR solution structure. Organic & Biomolecular Chemistry 2013, 11 (16), 2638-2647.

77) Meyer, A. ; Vasseur, J.-J. ; Morvan, F., Synthesis of Monoconjugated and Multiply Conjugated Oligonucleotides by “Click Thiol” Thiol-Michael-Type Additions and by Combination with CuAAC “Click Huisgen”. European Journal of Organic Chemistry 2013, (3), 465-473.

76) Goudot, A. ; Pourceau, G. ; Meyer, A. ; Gehin, T. ; Vidal, S. ; Vasseur, J. J. ; Morvan, F. ; Souteyrand, E. ; Chevolot, Y., Quantitative analysis (Kd and IC50) of glycoconjugates interactions with a bacterial lectin on a carbohydrate microarray with DNA Direct Immobilization (DDI). Biosensors & Bioelectronics 2013, 40 (1), 153-160.

2012

75) Morvan, F. ; Vidal, S. ; Souteyrand, E. ; Chevolot, Y. ; Vasseur, J.-J., DNA glycoclusters and DNA-based carbohydrate microarrays : From design to applications. RSC Advances 2012, 2 (32), 12043-12068.

74) Selisko, B. ; Potisopon, S. ; Agred, R. ; Priet, S. ; Varlet, I. ; Thillier, Y. ; Sallamand, C. ; Debart, F. ; Vasseur, J.-J. ; Canard, B., Molecular Basis for Nucleotide Conservation at the Ends of the Dengue Virus Genome. PLoS Pathogens 2012, 8 (9), e1002912

73) Gerland, B. ; Goudot, A. ; Pourceau, G. ; Meyer, A. ; Vidal, S. ; Souteyrand, E. ; Vasseur, J.-J. ; Chevolot, Y. ; Morvan, F., Synthesis of Homo- and Heterofunctionalized Glycoclusters and Binding to Pseudomonas aeruginosa Lectins PA-IL and PA-IIL. The Journal of Organic Chemistry 2012, 77 (17), 7620-7626

72) Gerland, B. ; Goudot, A. ; Pourceau, G. ; Meyer, A. ; Dugas, V. ; Cecioni, S. ; Vidal, S. ; Souteyrand, E. ; Vasseur, J. J. ; Chevolot, Y. ; Morvan, F., Synthesis of a Library of Fucosylated Glycoclusters and Determination of their Binding toward Pseudomonas aeruginosa Lectin B (PA-IIL) Using a DNA-Based Carbohydrate Microarray. Bioconjugate Chemistry 2012, 23 (8), 1534-1547

71) Cantel, S. ; Brunel, L. ; Ohara, K. ; Enjalbal, C. ; Martinez, J. ; Vasseur, J. J. ; Smietana, M., An innovative strategy for sulfopeptides analysis using MALDI-TOF MS reflectron positive ion mode. Proteomics 2012, 12 (14), 2247-2257

70) El Amri, C. ; Martin, A. R. ; Vasseur, J.-J. ; Smietana, M., Borononucleotides as Substrates/Binders for Human NMP Kinases : Enzymatic and Spectroscopic Evaluation. ChemBioChem 2012, 13 (11), 1605-1612

69) Smietana, M. ; Martin, A. R. ; Vasseur, J. J., Dynamic boronic acid-mediated autoligation of DNA strands. Pure and Applied Chemistry 2012, 84 (7), 1659-1667.

68) Elayadi, H. ; Mesnaoui, M. ; Korba, B.E. ; Smietana, M. ; Vasseur, J. J. ; Secrist, J.A. ; Lazrek, H. B., Preparation of 1,4-disubstituted-1,2,3-triazolo ribonucleosides by Na2CuP2O7 catalyzed azide-alkyne 1,3-dipolar cycloaddition. Arkivoc 2012, (vi), 76-89

67) Thillier, Y. ; Decroly, E. ; Morvan, F. ; Canard, B. ; Vasseur, J.-J. ; Debart, F., Synthesis of 5’ cap-0 and cap-1 RNAs using solid-phase chemistry coupled with enzymatic methylation by human (guanine-N7)-methyl transferase. RNA 2012, 18 (4), 856-868.

66) Ligeour, C. ; Meyer, A. ; Vasseur, J.-J. ; Morvan, F., Bis- and Tris-Alkyne Phosphoramidites for Multiple 5′-Labeling of Oligonucleotides by Click Chemistry. European Journal of Organic Chemistry 2012, (9), 1851-1856.

2011

65) Pourceau, G. ; Chevolot, Y. ; Goudot, A. ; Giroux, F. ; Meyer, A. ; Moules, V. ; Lina, B. ; Cecioni, S. ; Vidal, B. ; Yu, H. ; Chen, X. ; Ferraris, O. ; Praly, J. P. ; Souteyrand, E. ; Vasseur, J. J. ; Morvan, F., Measurement of Enzymatic Activity and Specificity of Human and Avian Influenza Neuraminidases from Whole Virus by Glycoarray and MALDI-TOF Mass Spectrometry. Chembiochem 2011, 12 (13), 2071-2080

64) Chevolot, Y. ; Zhang, J. ; Meyer, A. ; Goudot, A. ; Rouanet, S. ; Vidal, S. ; Pourceau, G. ; Cloarec, J.-P. ; Praly, J.-P. ; Souteyrand, E. ; Vasseur, J.-J. ; Morvan, F., Multiplexed binding determination of seven glycoconjugates for Pseudomonas aeruginosa Lectin I (PA-IL) using a DNA-based carbohydrate microarray. Chemical Communications 2011, 47 (31), 8826-8828

63) Boissonnet, A. ; Dupouy, C. ; Millard, P. ; Durrieu, M. P. ; Tarrat, N. ; Escudier, J. M., alpha,beta-D-CNA featuring canonical and noncanonical alpha/beta torsional angles behaviours within oligonucleotides. New J. Chem 2011, 35 (7), 1528-1533

62) Lavergne, T. ; Baraguey, C. ; Dupouy, C. ; Parey, N. ; Wuensche, W. ; Sczakiel, G. ; Vasseur, J.-J. ; Debart, F., Synthesis and Preliminary Evaluation of pro-RNA 2′-O-Masked with Biolabile Pivaloyloxymethyl Groups in an RNA Interference Assay. The Journal of Organic Chemistry 2011, 76 (14), 5719-5731.

61) Martin, A. R. ; Mohanan, K. ; Toupet, L. ; Vasseur, J.-J. ; Smietana, M., Regioselective Synthesis of 3-Carbo-5-phosphonylpyrazoles through a One-Pot Claisen–Schmidt/1,3-Dipolar Cycloaddition/Oxidation Sequence. European Journal of Organic Chemistry 2011, 2011 (17), 3184-3190.

60) Martin, A. R. ; Barvik, I. ; Luvino, D. ; Smietana, M. ; Vasseur, J.-J., Dynamic and Programmable DNA-Templated Boronic Ester Formation. Angewandte Chemie International Edition 2011, 50 (18), 4193-4196.

59) Chatelain, G. ; Meyer, A. ; Morvan, F. ; Vasseur, J. J. ; Chaix, C., Electrochemical detection of nucleic acids using pentaferrocenyl phosphoramidate alpha-oligonucleotides. New J. Chem 2011, 35 (4), 893-901.

2010

58) Jouanneau, D. ; Guibet, M. ; Boulenguer, P. ; Mazoyer, J. ; Smietana, M. ; Helbert, W., New insights into the structure of hybrid -/µ-carrageenan and its alkaline conversion. Food Hydrocolloids 2010, 24, 452-461.

57) Fraternale, A. ; Paoletti, M.F. ; Dominici, S. ; Caputo, A. ; Castaldello, A. ; Millo, E. ; Brocca-Cofano, E. ; Smietana, M. ; Clayette, P. ; Oiry, J. ; Benatti, U. ; Magnani, M., The increase in intra-macrophage thiols induced by new pro-GSH molecules directs the Th1 skewing in ovalbumin immunized mice. Vaccine 2010, 28, 7676-7682.

56) Dupouy, C. ; Millard, P. ; Boissonnet, Escudier, J.-M., “alpha,beta-D-CNA preorganization of unpaired loop moiety stabilizes DNA hairpin. Chemical Communications 2010, 46, 5142-5144.

55) Dupouy, C. ; Zhang, C. ; Padilla, A. ; Pochet, S. ; Kaminski, P. A., Probing the active site of the deoxynucleotide N-hydrolase Rcl encoded by the rat gene c6orf108. Journal of Biological Chemistry 2010, 285 (53), 41806-41814.

54) Elayadi, H. ; Smietana, M. ; Pannecouque, C. ; Leyssen, P. ; Neyts, J. ; Vasseur, J. J. ; Lazrek, H. B., Straightforward synthesis of triazoloacyclonucleotide phosphonates as potential HCV inhibitors. Bioorganic & Medicinal Chemistry Letters 2010, 20 (24), 7365-7368.

53) Meyer, A. ; Pourceau, G. ; Vasseur, J. J. ; Morvan, F. 5’-Bis-conjugation of Oligonucleotides by Amidative Oxidation and Click-Chemistry. Journal of Organic Chemistry, 2010, 75, (19), 6689-6692.

52) Priet, S. ; Zlatev, I. ; Barvik, I. ; Geerts, K. ; Leyssen, P. ; Neyts, J. ; Dutartre, H. ; Canard, B. ; Vasseur, J. J. ; Morvan, F. ; Alvarez, K., 3’-Deoxy Phosphoramidate Dinucleosides as Improved Inhibitors of Hepatitis C Virus Subgenomic Replicon and NS5B Polymerase Activity. Journal of Medicinal Chemistry, 2010, 53, (18), 6608-6617.

51) Pourceau, G. ; Meyer, A. ; Chevolot, Y. ; Souteyrand, E. ; Vasseur, J. J. ; Morvan, F., Oligonucleotide Carbohydrate-Centered Galactosyl Cluster Conjugates Synthesized by Click and Phosphoramidite Chemistries. Bioconjugate Chemistry, 2010, 21, (8), 1520-1529.

50) Meyer, A. ; Spinelli, N. ; Dumy, P. ; Vasseur, J. J. ; Morvan, F. ; Defrancq, E., Oligonucleotide Sequential Bis-Conjugation via Click-Oxime and Click-Huisgen Procedures. Journal of Organic Chemistry, 2010, 75, (11), 3927-3930.

49) Baddi, L. ; Smietana, M. ; Sebti, S. ; Vasseur, J. J. ; Lazrek, H. B., A Procedure for Facile Synthesis of Nucleosides Using N, O-Bistrimethylsilylacetamide in the Presence of Natural Phosphate Coated with Potassium Iodide. Letters in Organic Chemistry, 2010, 7, (3), 196-199.

48) Zlatev, I. ; Lavergne, T. ; Debart, F. ; Vasseur, J.-J. ; Manoharan, M. ; Morvan, F., Efficient Solid-Phase Chemical Synthesis of 5’-Triphosphates of DNA, RNA, and their Analogues. Organic Letters, 2010, 12, (10), 2190-2193.

47) Mohanan, K. ; Martin, A. R. ; Toupet, L. ; Smietana, M. ; Vasseur, J.-J., Three-Component Reaction Using the Bestmann-Ohira Reagent : A Regioselective Synthesis of Phosphonyl Pyrazole Rings13. Angewandte Chemie International Edition, 2010, 49, (18), 3196-3199.

46) Morvan, F. ; Debart, F. ; Vasseur, J.-J., From anionic to cationic alpha anomeric oligodeoxynucleotides. Chemistry & Biodiversity, 2010, 7, (3), 494-535.

2009

45) Zhang, J. ; Pourceau, G. ; Meyer, A. ; Vidal, S. ; Praly, J. P. ; Souteyrand, E. ; Vasseur, J. J. ; Morvan, F. ; Chevolot, Y., Specific recognition of lectins by oligonucleotide glycoconjugates and sorting on a DNA microarray. Chemical Communications, 2009, (44), 6795-6797.

44) Martin, A.R. ; Mohanan, K. ; Luvino, D. ; Floquet, N. ; Baraguey, C. ; Smietana, M. ; Vasseur, J.-J., Expanding the borononucleotide family : synthesis of boronoanalogues of dCMP, dGMP and dAMP. Organic and Biomolecular Chemistry, 2009, 7, (21), 4369-4377.

43) Zlatev, I. ; GirautT, F. ; Morvan, F. ; Herdewijn, P. ; Vasseur, J.-J., delta-Di-Carboxybutyl Phosphoramidate of 2’-Deoxycytidine-5’-Monophosphate as Substrate for DNA Polymerization by HIV-1 Reverse Transcriptase. Bioorganic and Medicinal Chemistry, 2009, 17, (19), 7008-7014.

42) Pourceau, G. ; Meyer, A. ; Vasseur, J.-J. ; Morvan, F., Azide solid support for 3’-conjugation of oligonucleotides and their circularization by click chemistry. Journal of Organic Chemistry, 2009, 74, (17), 6837-6842.

41) Martin, A. R. ; Lavergne, T. ; Vasseur, J.-J. ; Debart, F., Assessment of new 2’-O-acetalester protecting groups for regular RNA synthesis and original 2’-modified proRNA. Bioorganic & Medicinal Chemistry Letters 2009, 19, (15), 4046-4049.

40) Moni, L.. ; Pourceau, G. ; Zhang, J. ; Meyer, A. ; Vidal, S. ; Souteyrand, E. ; Dondoni, A. ; Morvan, F. ; Chevolot, Y. ; Vasseur, J.-J. ; Marra, A., Design of triazole-tethered glycoclusters exhibiting three different spatial arangements and comparative study of their affinity for PA-IL and RCA 120 using a DNA-based Glycoraray. ChemBioChem 2009, 10, (8), 1369-1378.

39) Zhang, J. ; Pourceau, G. ; Meyer, A. ; Vidal, S. ; Praly, J.-P. ; Souteyrand, E. ; Vasseur, J.-J. ; Morvan, F. ; Chevolot, Y., DNA-directed immobilisation of glycomimetics for glycoarrays application : Comparison with covalent immobilisation, and development of an on-chip IC50 measurement assay. Biosensors and Bioelectronics 2009, 24, 2515-2521.

38) Lavergne, T. ; Parey, N. ; Debart, F. ; Vasseur, J.-J., Efficient Release of Base-Sensitive Oligonucleotides from Solid Supports Using Fluoride Ions. European Journal of Organic Chemistry 2009, (13), 2190-2194.

37) Ohara, K. ; Vasseur, J.-J. ; Smietana, M., NIS-promoted guanylation of amines. Tetrahedron Letters 2009, 50, (13), 1463-1465.

36) Pourceau, G. ; Meyer, A. ; Vasseur, J. J. ; Morvan, F., Synthesis of Mannose and Galactose Oligonucleotide Conjugates by Bi-click chemistry. Journal of Organic Chemistry 2009, 74, (3), 1218-1222.

35) Ohara, K. ; Jacquinet, J.-C. ; Jouanneau, D. ; Helbert, W. ; Smietana, M. ; Vasseur, J.-J., Matrix-Assisted Laser Desorption/Ionization Mass Spectrometric Analysis of Polysulfated-derived Oligosaccharides Using Pyrenemethylguanidine. Journal of the American Society for Mass Spectrometry 2009, 20, 131-137.

2008

34) Luvino, D. ; Gasparutto, D. ; Reynaud, S. ; Smietana, M. ; Vasseur, J.-J., Boronic acid-based fluorescent receptors for selective recognition of thymine glycol. Tetrahedron Letters 2008, 49, (42), 6075-6078.

33) Zlatev, I. ; Dutartre, H. ; Barvik, I. ; Neyts, J. ; Canard, B. ; Vasseur, J.-J. ; Alvarez, K. ; Morvan, F., Phosphoramidate Dinucleosides as Hepatitis C Virus Polymerase Inhibitors. J. Med. Chem. 2008, 51, (18), 5745-5757.

32) Pourceau, G. ; Meyer, A. ; Vasseur, J. J. ; Morvan, F., Combinatorial and automated synthesis of phosphodiester galactosyl cluster on solid support by click chemistry assisted by microwaves. Journal of Organic Chemistry 2008, 73, (15), 6014-6017.

31) Smietana, M. ; Clayette, P. ; Mialocq, P. ; Vasseur, J. J. ; Oiry, J., Synthesis of new N-isobutyryl-L-cysteine/MEA conjugates : Evaluation of their free radical-scavenging activities and anti-HIV properties in human macrophages. Bioorganic Chemistry 2008, 36, (1-3), 133-140.

30) Luvino, D. ; Baraguey, C. ; Smietana, M. ; Vasseur, J. J., Borononucleotides : synthesis, and formation of a new reversible boronate internucleosidic linkage. Chemical Communications 2008, (20), 2352-2354.

29) Zlatev, I. ; Vasseur, J.-J. ; Morvan, F., Deoxygenation of 5-O-benzoyl-1,2-isopropylidene-3-O-imidazolylthiocarbonyl-[alpha]-d-xylofuranose using dimethyl phosphite : an efficient alternate method towards a 3’-deoxynucleoside glycosyl donor. Tetrahedron Letters 2008, 49, (20), 3288-3290.

28) Fratemale, A. ; Paoletti, M. F. ; Casabianca, A. ; Orlandi, C. ; Schiavano, G. F. ; Chiarantini, L. ; Clayette, P. ; Oiry, J. ; Vogel, J. U. ; Cinatl, J. ; Magnani, M., Inhibition of murine AIDS by pro-glutathione (GSH) molecules. Antiviral Research 2008, 77, (2), 120-127.

27) Lavergne, T. ; Bertrand, J. R. ; Vasseur, J. J. ; Debart, F., A Base-Labile Group for 2 ‘-OH Protection of Ribonucleosides : A Major Challenge for RNA Synthesis. Chemistry a European Journal 2008, 14, (30), 9135-9138.

26) Lietard, J. ; Meyer, A. ; Vasseur, J. J. ; Morvan, F., New strategies for cyclization and bicyclization of oligonucleotides by click chemistry assisted by microwaves. Journal of Organic Chemistry 2008, 73, (1), 191-200.

25) Mourgues, S. ; Trzcionka, J. ; Vasseur, J. J. ; Pratviel, G. ; Meunier, B., Incorporation of Oxidized Guanine Nucleoside 5’ ;-Triphosphates in DNA with DNA Polymerases and Preparation of Single-Lesion Carrying DNA. Biochemistry 2008, 47, (16), 4788-4799.

2007

24) Ohara, K. ; Smietana, M. ; Restouin, A. ; Mollard, S. ; Borg, J. P. ; Collette, Y. ; Vasseur, J. J., Amine-guanidine switch : A promising approach to improve DNA binding and antiproliferative activities. Journal of Medicinal Chemistry 2007, 50, (26), 6465-6475.

23) Zlatev, I. ; Vasseur, J.-J. ; Morvan, F., Convenient synthesis of N2-isobutyryl-2’-O-methyl guanosine by efficient alkylation of O6-trimethylsilylethyl-3’,5’-di-tert-butylsilanediyl guanosine. Tetrahedron 2007, 63, (45), 11174-11178.

22) Perzyna, A. ; Zotto, C. ; Durand, J. O. ; Granier, M. ; Smietana, M. ; MeInyk, O. ; Stara, I. G. ; Stary, I. ; Klepetarova, B. ; Saman, D., Reaction of isocyanate-functionalised silicon wafers with complex amino compounds. European Journal of Organic Chemistry 2007, (24), 4032-4037.

21) Lietard, J. ; Meyer, A. ; Vasseur, J. J. ; Morvan, F., An efficient reagent for 5 ‘-azido oligonucleotide synthesis. Tetrahedron Letters 2007, 48, (50), 8795-8798.

20) Luvino, D. ; Amalric, C. ; Smietana, M. ; Vasseur, J. J., Sequential Seyferth-Gilbert/CuAAC reactions : Application to the one-pot synthesis of triazoles from aldehydes. Synlett 2007, (19), 3037-3041.

19) Moukha-Chafiq, O. ; Taha, M. L. ; Mouna, A. ; Lazrek, H. B. ; Vasseur, J. J., Synthesis and biological evaluation of some alpha-[6-(1 ‘-carbamoylalkylthio)-1H-pyrazolo[3,4-D]pyrimidin-4-yl]thioalkylcarboxamide acyclonucleosides. Nucleosides Nucleotides & Nucleic Acids 2007, 26, (4), 335-345.

18) Froeyen, M. ; Morvan, F. ; Vasseur, J. J. ; Nielsen, P. ; Van Aerschot, A. ; Rosemeyer, H. ; Herdewijn, P., Conformational and Chiral Selection of Oligonucleotides. Chemistry & Biodiversity 2007, 4, 803-817.

17) Peyrane, F. ; Selisko, B. ; Decroly, E. ; Vasseur, J. J. ; Benarroch, D. ; Canard, B. ; Alvarez, K., High-yield production of short GpppA- and 7MeGpppA-capped RNAs and HPLC-monitoring of methyltransfer reactions at the guanine-N7 and adenosine-2’-O positions. Nucleic Acids Research 2007, 35, (4), 1-11.

16) Deglane, G. ; Morvan, F. ; Debart, F. ; Vasseur, J.-J., 5-propynylamino alpha-deoxyuridine promotes DNA duplex stabilization of anionic and neutral but not cationic alpha-oligonucleotides. Bioorganic and Medicinal Chemistry Letters 2007, 17, 951-954.

15) Chevolot, Y. ; Bouillon, C. ; Vidal, S. ; Morvan, F. ; Meyer, A. ; Cloarec, J. P. ; Jochum, A. ; Praly, J. P. ; Vasseur, J.-J. ; Souteyrand, E., DNA-based carbohydrate biochips : a platform for surface glyco-engineering. Angewandte Chemie International Edition 2007, 46, 2398-2402.

14) Debart, F. ; Abes, S. ; Deglane, G. ; Moulton, H. M. ; Clair, P. ; Gait, M. J. ; Vasseur, J. J. ; Lebleu, B., Chemical modifications to improve the cellular uptake of oligonucleotides. Current Topics in Medicinal Chemistry 2007, 7, (7), 727-737.

13) Morvan, F. ; Meyer, A. ; Jochum, A. ; Sabin, C. ; Chevolot, Y. ; Imberty, A. ; Praly, J. P. ; Vasseur, J. J. ; Souteyrand, E. ; Vidal, S., Fucosylated pentaerythrityl phosphodiester oligomers (PePOs) : Automated synthesis of DNA-Based glycoclusters and binding to Pseudomonas aeruginosa lectin (PA-IIL). Bioconjugate Chemistry 2007, 18, (5), 1637-1643.

2006

12) Lazrek, H. B. ; Ouzebla, D. ; Rochdi, A. ; Redwane, N. ; Vasseur, J. J., A one-pot synthesis of D-ribonucleosides using natural phosphate doped with KI in HMDS. Letters in Organic Chemistry 2006, 3, (4), 313-314.

11) Luvino, D. ; Smietana, M. ; Vasseur, J. J., Selective fluorescence-based detection of dihydrouridine with boronic acids. Tetrahedron Letters 2006, 47, (52), 9253-9256.

10) Zlatev, I. ; Kato, Y. ; Meyer, A. ; Vasseur, J. J. ; Morvan, F., Use of a solid-supported coupling reagent for a selective phosphitylation of the primary alcohol of N-2-isobutyryl-2’-deoxy or 2 ‘-O-methyl guanosine. Tetrahedron Letters 2006, 47, (47), 8379-8382.

9) Meyer, A. ; Bouillon, C. ; Vidal, S. ; Vasseur, J. J. ; Morvan, F., A versatile reagent for the synthesis of 5 ‘-phosphorylated, 5 ‘-thiophosphorylated or 5 ‘-phosphoramidate-conjugated oligonucleotides. Tetrahedron Letters 2006, 47, (50), 8867-8871.

8) Adamo, I. ; Dueymes, U. ; Schonberger, A. ; Navarro, A. E. ; Meyer, A. ; Lange, M. ; Imbach, J. L. ; Link, F. ; Morvan, F. ; Vasseur, J. J., Solution-phase synthesis of phosphorothioate oligonucleotides using a solid-supported acyl chloride with H-phosphonate chemistry. European Journal of Organic Chemistry 2006, (2), 436-448.

7) Moukha-Chafiq, O. ; Taha, M. L. ; Lazrek, H. B. ; Vasseur, J. J. ; Clercq, E. D., Synthesis and antiviral activity of some C2-, C4-, and C6-substituted pyrazolo[3,4-D]pyrimidine acyclonucleosides with the alkylating chains of ACV, HBG, and ISO-DHPG. Nucleosides Nucleotides Nucleic Acids. 2006, 25, (8), 849-860.

6) Ohara, K. ; Smietana, M. ; Vasseur, J. J., Characterization of specific noncovalent complexes between guanidinium derivatives and single-stranded DNA by MALDI. J Am Soc Mass Spectrom. 2006, 17, (3), 283-291.

5) Fraternale, A. ; Paoletti, M. F. ; Casabianca, A. ; Oiry, J. ; Clayette, P. ; Vogel, J. U. ; Cinatl, J., Jr. ; Palamara, A. T. ; Sgarbanti, R. ; Garaci, E. ; Millo, E. ; Benatti, U. ; Magnani, M., Antiviral and immunomodulatory properties of new pro-glutathione (GSH) molecules. Curr Med Chem. 2006, 13, (15), 1749-1755.

4) Bouillon, C. ; Meyer, A. ; Vidal, S. ; Jochum, A. ; Chevolot, Y. ; Cloarec, J. P. ; Praly, J. P. ; Vasseur, J. J. ; Morvan, F., Microwave assisted “click” chemistry for the synthesis of multiple labeled-carbohydrate oligonucleotides on solid support. J Org Chem. 2006, 71, (12), 4700-4702.

3) Deglane, G. ; Abes, S. ; Michel, T. ; Prevot, P. ; Vives, E. ; Debart, F. ; Barvik, I. ; Lebleu, B. ; Vasseur, J. J., Impact of the guanidinium group on hybridization and cellular uptake of cationic oligonucleotides. Chembiochem. 2006, 7, (4), 684-692.

2) Johnson, A. A. ; Sayer, J. M. ; Yagi, H. ; Patil, S. S. ; Debart, F. ; Maier, M. A. ; Corey, D. R. ; Vasseur, J. J. ; Burke, T. R., Jr. ; Marquez, V. E. ; Jerina, D. M. ; Pommier, Y., Effect of DNA modifications on DNA processing by HIV-1 integrase and inhibitor binding : role of DNA backbone flexibility and an open catalytic site. J Biol Chem. 2006, 281, (43), 32428-32438.

1) Parey, N. ; Baraguey, C. ; Vasseur, J. J. ; Debart, F., First evaluation of acyloxymethyl or acylthiomethyl groups as biolabile 2’-O-protections of RNA. Org Lett. 2006, 8, (17), 3869-3872.

b) Chapitres dans des ouvrages

14) Thillier, y. ; Morvan, F. ; Vasseur, J.-J. ; Debart, F.,« Innovative chemistry for synthesis of regular RNA, 5’-triphosphate RNA, or 5’-capped RNA » in « Chemical Biology of Nucleic Acids », A., E. V. ; Markiewicz, W. T. ; Barciszewski, J., Eds. Springer : Berlin Heidelberg, pp 563-589 (2014).

13) Zlatev, I. ; Manoharan, M. ; Vasseur, J.-J. ; Morvan, F.,« Solid-Phase Chemical Synthesis of 5’-triphosphate DNA, RNA and Chemically Modified Oligonucleotides » in « Current Protocols in Nucleic Acid Chemistry », Eds S.L. Beaucage, D.E. Bergstrom, P. Herdewijn, A. Matsuda, Wiley, 2012, 1:1.28.1–1.28.16. en ligne DOI : 10.1002/0471142700.nc0128s50.

12) Smietana, M. ; Vasseur, J.-J. ; Cossy, J. ; Arseniyadis, S., « DNA as a tool for molecular discovery. » in « Modern tools for the synthesis of complex bioactive molecules », Eds S. Arseniyadis, J. Cossy, John Wiley & sons, Inc., 2012, 539-555.

11) Morvan, F. ; Debart, F. ; Vasseur, J.-J., « From Anionic to Cationic Alpha-Anomeric-Oligodeoxynucleotides », in « Chemistry end Biology of Artificial Nucleic Acids », Eds Egli, M. ; Herdewijn, P., Verlag Helvetica Chemica Acta, Zürich, Switzerland and Wiley-VCH, Weinheim, Federal Republic of Germany, 2012, pp 79-120.

10) Pourceau, G. ; Meyer A. ; Vasseur, J.-J. ; Morvan, F.,« Synthesis of a Glycomimetic Oligonucleotide Conjugate by 1,3-Dipolar Cycloaddition », in « Bioconjugation Protocols : Strategies and Methods », Ed Mark, S. S., Springer : New York, Dordrecht, Heidelberg, London, 2011, Vol. 751 ; pp 167-193.

9) Morvan, F. ; Chevolot, Y. ; Zhang, J. ; Meyer, A. ; Vidal, S. ; Praly, J.-P. ; Vasseur, J.-J. ; Souteyrand, E., « Glycoarray by DNA-Directed Immobilization. » In Methods in molecular biology (Clifton, N.J.), 2012 ; Vol. 808, pp 195-219.

8) Chevolot, Y. ; Vidal, S. ; Laurenceau, E. ; Morvan, F. ; Vasseur, J.-J. ; Souteyrand, E.,« Carbohydrates as recognition receptors in biosensing applications », in « Recognition Receptors in Biosensors », Ed Zourob, M. Springer : New York, Dordrecht, Heidelberg, London, 2010, pp 275-341.

7) Lavergne, T. ; Janin, M. ; Dupouy, C. ; Vasseur, J.-J. ; Debart, F.,« Chemical Synthesis of RNA with Base-Labile 2’-O-(Pivaloyloxymethyl)-Protected Ribonucleoside Phosphoramidites », in « Current Protocols in Nucleic Acid Chemistry », Beaucage, S. ; Bergstrom, D. ; Herdewijn, P. ; Matsuda, A., Eds John Wiley & Sons, Inc. : 2010 ; pp 3.19.1-3.19.27.

6) Pourceau, G. ; Meyer, A. ; Vasseur, J.-J. ; Morvan, F.,« Carbohydrate-Oligonucleotide Conjugates », in « Current Protocols in Nucleic Acid Chemistry », Beaucage, S. ; Bergstrom, D. ; Herdewijn, P. ; Matsuda, A.,Eds John Wiley & Sons, Inc. : 2009 ; pp 4.38.1-4.38.25.

5) Chevolot, Y. ; Vidal, S. ; Laurenceau, E. ; Morvan, F. ; Vasseur, J.-J. ; Souteyrand, E.,« Carbohydrates as recognition receptors in biosensing applications », in « Recognition reception in biosensors », Eds M. Zourob, Spinger, 2009, châp. 7, pages 271-336

4) Smietana, M. ; Ohara, K. ; Vasseur, J.-J., « MALDI-TOF Detection of Specific Noncovalent Complexes of Highly Acidic Biomolecules with Pyrenemethylguanidinium » in « Mass Spectrometry of Nucleosides and Nucleic Acids » Eds J. Banoub, P. A. Limbach, CRC Press, 25 oct. 2009

3) Froeyen, M. ; Morvan, F. ; Vasseur, J. J. ; Nielsen, P. ; Van Aerschot, A. ; Rosemeyer, H. ; Herdewijn, P., “Conformational and Chiral Selection of Oligonucleotides”, in “Origin of life : chemical approach”, Eds P. Herdewijn, M.V. Kisakürek, Wiley, 2008, 25.

2) Morvan, F. ; Meyer, A. ; Vasseur, J.-J.,”Universal and recyclable solid support for oligonucleotides synthesis”, in “Current Protocols in Nucleic Acid Chemistry”, Eds S.L. Beaucage, D.E. Bergstrom, P. Herdewijn, A. Matsuda, Wiley, 2007, 3.16.1-3.16.19.

1) Morvan, F. ; Vasseur, J.-J.,”Solution-Phase Synthesis of Di- and Trinucleotides using Polymer-Supported Reagents”, in “Current Protocols in Nucleic Acid Chemistry”, Eds S.L. Beaucage, D.E. Bergstrom, P. Herdewijn, A. Matsuda, Wiley, 2006, 3.14.1-3.14.15.

c) Brevets

9) « Glycoclusters and their Pharmaceutical Use as Antibacterials » F. Morvan, J.-J. Vasseur, C. Ligeour, Y. Chevolot, E. Souteyrand, O. Vidal, A. Goudot, S. Vidal. WO 2015-040209 A1 020150326, EP 2851 371 A, publié le 25 mars 2015.

8) « Oligonucléotides modifiés comprenant des fonctions thiol et leur utilisation pour la détection d´acides nucléiques » F. Morvan, A. Meyer, J.-J. Vasseur, J. Mayen, C. Chaix, C. Farre, C. Fournier-Wirth, J.-F. Cantaloube, M. Lereau. Demande PCT international PCT/EP2013/057150 le 4 avril 2013, WO 2013/150122 A1, publié le 10/10/2013, US 2015/0232957 A1, August 20, 2015.

7) « Composés thiols et leur utilisation pour la synthèse d´oligonucleotides modifiés » F. Morvan, A. Meyer, J.-J. Vasseur, J. Mayen, C. Chaix, C. Farre, C. Fournier-Wirth, J.-F. Cantaloube, M. Lereau. Demande PCT international PCT/EP2013/057122 le 4 avril 2013, WO 2013/150106 A1, publié le 10/10/2013, US 2015/0158964 A1, June 11, 2015, Non exclusive licence agreement N° CNRS L15034 CNRS-UCBL-UM-EFS-Chemgenes Corp., 20 mai 2015.
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6) « Chemical RNA synthesis method », F. Debart, J.J. Vasseur, .T. Lavergne, PCT/FR2009/000624 (May 28, 2009), Pub. N° : US2011/0275793 A1, Publication date : Nov. 10, 2011

5) « Method for the Synthesis of Oligonucleotide Derivatives », F. Morvan, A. Meyer, J.J. Vasseur, S. Vidal, J.-P. Cloarec, Y. Chevolot, E. Souteyrand, CNRS, WO2007125429, publié le 08/11/2007, PCT/US7,951,926 B2 (May 31, 2011) et le 06/10/2011, N° : US2011/0245478 A1, Publication date : Oct. 6, 2011

4) « Process for Triphosphate Oligonucleotide Synthesis », I. Zlatev, F. Morvan, J.J. Vasseur, F. Debart, M. Manoharan, Alnylam Pharmaceutical Inc. / CNRS, WO2011/028218 A1 du 10 mars 2011, PCT/US2009/0055775 (02/09/2009), US 9,035,041 B2, May 19, 2015.

3) « Methode de Synthèse d’ARN », T. Lavergne, J.J. Vasseur, F. Debart FR08 02928, 2008.

2) « Method for preparing oligonucleotides », I. Adamo, C. Dueymes, A. Schoenberger, J.L. Imbach, A. Meyer, F. Morvan, F. Debart, J.J. Vasseur, .M. Lange, F. Link, International Application, WO2004/013154 A1 du 12 Février 2004, US Patent Application 2006/00894994 A1 No : 10/522,854 du 27 Avril 2006, US2011/0224424 A1, Publication date : Sept. 15, 2011

1) « Antioxidants, Preparation Methods and Uses », J. Oiry, J.-Y Puy, J.-L. Imbach, P. Clayette, P. Fretier., US Patent (CNRS/CEA) N° 6,989,372 B1 – Jan. 24, 2006.

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