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Synthèse de Lipides Bioactifs : publications de l’équipe/Brevets

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Liste publications/brevets 2018-2023

Articles published in peer reviews
Nrf2-mediated Antioxidant Defense and Peroxiredoxin 6 are Linked to Biosynthesis of Palmitic Acid Ester of 9-Hydroxystearic Acid
O. Kuda, M. Brezinova, J. Silhavy, V. Landa, V. Zidek, C. Dodia, F. Kreuchwig, M. Vrbacky, L. Balas, T. Durand, N. Hubner, A. B. Fisher, J. Kopecky, M. Pravenec
Diabetes, 2018, 67, 1190-1197.

F2-isoprostanes affect macrophage migration and CSF-1 Signaling
J. M. Proodfoot, F.J. Pixley, E.L. Greenland, A.E. Barden, K.D. Croft, J-M. Galano, T. Durand, T. Mori
Free Radic Biol Med 2018,126, 142-152.

Sorting out the phytoprostane and phytofuran profile in vegetable oils
R. Dominguez-Perles, F. Ferreres, A. Guy, J-M. Galano, C. Oger, T. Durand, A. Gil-Izquierdo
Food Res Inter2018, 107, 619-628.

Ultra-Performance Liquid Chromatography-Mass Spectrometry Analysis of Free and Esterified Oxygenated Derivatives from Docosahexaenoic Acid in Rat Brain
Ch. Jouvène, B. Fourmaux, A. Géloën, L. Balas, T. Durand, M. Lagarde, M. Létisse, M. Guichardant
Lipids, 2018, 53, 103-116.

Aronia-citrus juice intake (polyphenol rich juice) and elite triathlon training : A lipidomic approach using representative oxylipins in urine.
García-Flores, L. A. ; Medina, S. ; Gomez, C. ; Wheelock, C.E. ; Cejuela, R. ; Martínez-Sanz, J.M. ; Oger, C. ; Galano, J.-M. ; Durand, T. ; Martínez-Hernández, P. ; Ferreres, F. ; Gil, P. ; Gil-Izquierdo, A.
Food Funct. 2018, 9 463-475.

Development of an LC-(ESI-)-MS/MS method for the simultaneous quantification of 35 isoprostanes and isofurans derived from the major n3 and n6 PUFAs
KM Rund, AI Ostermann, LKutzner, J-M Galano, C Oger, C Vigor, S Wecklein, N Seiwert, T Durand, NH Schebb
Anal Chim Acta 2018, 1037,63-74.

Relevance of 4-F4t-neuroprostane and 10-F4t-neuroprostane to neurological diseases.
C. Signorini, C. De Felice, T. Durand, J-M. Galano, C. Oger, S. Leoncini, M. Carone, M. Ulivelli, C. Manna, A. Cortelazzo, J. C.Y. Lee, J. Hayek
Free Radic Biol Med 2018,115, 278-287.

Oxidized LDL triggers changes oxidative stress and inflamation biomarkers in human macrophages
O. L. lara-Guzman, A. Gil-Izquierdo, S. Medina, E. Osorio, R. Alvarez, C. Oger, T. Durand, J-M.Galano, N. Zuluaga, K. Munoz-Durango
Redox Biol. 2018, 15, 1-11

Levels of palmitic acid ester of hydroxystearic acid (PAHSA) are reduced in the breast milk of obese mothers
M. Brezinova, O. Kuda, J. Hansikova, M. Rombaldova, L. Balas, K. Bardova, T. Durand, M. Rossmeisl, M. Cerna, Z. Stranak, Y. Kopecky
BBA – Molecular and Cell Biology of Lipids 2018, 1863,126-131.

Effects of Cyclic Fatty Acid Monomers from Heated Vegetable Oil on Markers of Inflammation and Oxidative Stress in Male Wistar Rats
J. Mboma, P. Angers, N. Leblanc, A. Rocher, C. Vigor, C. Oger, G. Reversat, J. Vercauteren, J-M. Galano, T. Durand, H. Jacques
J Agric Food Chem 2018, 66, 7122-7180

154 – Isoprostanoids quantitative profiling of marine red and brown macroalgae
C. Vigor, C. Oger, G. Reversat, A. Rocher, J. Vercauteren, J-M. Galano, T. Durand, T. Tonon, C. Leblanc, P. Potin
Food Chem. 2018, 268, 452-462.

155 - Dietary Oat Bran Increases Some Proinflammatory Polyunsaturated Fatty-Acid Oxidation Products and Reduces
Anti-Inflammatory Products in Apolipoprotein E−/− Mice
J C-Y Lee, D S. AlGhawas, K Poutanen, K S Leung, J-M Galano, C Oger, T Durand, H El-Nezami
Lipids 2018, 53, 785-796.

156 - Resveratrol-Linoleate inhibits the pathological endothelial permeability via a drastic reduction of the MMP-9 activity
A. Shamseddin, C. Crauste, E. Durand, P. Villeneuve, G. Dubois, T. Pavlickova,T. Durand, J. Vercauteren and F. Veas
Biosci Reports 2018,38, BSR20171712.

Reliable analytical method to determine new lipid peroxidation biomarkers in urine samples : Application to Mild Cognitive Impairment due to Alzheimer Disease
A. Garcia-Blanco, C. Pena-Bautista, C. Oger, C. Vigor, J-M. Galano, T. Durand, N. Martin-Ibanez, M. Baquero, M. Vento, C. Chafer-Pericas
Talanta 2018, 184, 193-201.

Simultenous determination of PUFA-derived pro-resolving metabolites and pathway markers unsing chiral chromatography and tandem mas spectrometry
A. Toewe, L. Balas,T. Durand, G. Geisslinger, N. Ferreiros
Anal Chim Acta 2018, 1031, 185-194.

Plasma lipid peroxidation biomarkers for early and non-invasive Alzheimer Disease detection.
C. Péna-Baitista, C. Vigor, J-M. Galano, C. Oger, T. Durand, I. Ferrer, A. Cuevas, R Lopez, M. Baquero, M. Lopez-Nogueroles, M. Vento, D. Hervas, A. Garcia-Blanco, C. Chafer-Pericas
Free Radic Biol Med 2018, 124, 388-394.

Impact on phytoprostane and phytofuran (stress biomarkers) content of salicylic acid and growing environment on Oryza sativa L
Pinciroli, M., Domínguez-Perles, R., Garbi, M., Abellán, A., Oger C.,Durand. T., Galano, J.M., Gil-Izquierdo, A.
J Agric Food Chem 2018, 66, 12561-12570.

Cyclooxygenase and lipoxygenases are used by the fungus Podospora anserina to repel nematodes
R. Ferrari, I. Lacaze, P. Le Faouder, J. Bertand-Michel, C. Oger, J-M. Galano, T. Durand, S. Moularat, L. Chan To Hong, C. Boucher, J. Kilani, Y. Petit, O. Vanparis, C. Trannoy, S. Brun, H. Lalucque, F. Malagnac, P. Silar
BBA General Subject 2018, 1862, 2174-2182.

Non-enzymatic synthesis of bioactive isoprostanoids in the Diatom Phaeodactylum following oxidative stress.
J. Lupete, A. Jaussaud, C. Vigor, C. Oger, J-M. Galano, G. Réversat, J. Vercauteren, J. Jouhet, T. Durand, E. Marechal
Plant Physiol. 2018, 178, 1344-1357.

Profiling of omega-polyunsaturated fatty acids and its oxidized products in salmon after different cooking methods
K. S. Leung, J-M. Galano, T. Durand, J. C. Y. Lee
Antioxidants 2018, 7, 96

Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis
Nguyen, Phuong C. ; Delorme, V. ; Benarouche, A. ; Guy, A. ; Landry, V. ; Audebert, S. ; Pophilat, M. ; Camoin, L. ; Crauste, C. ; Galano, J-M. ; Durand, T. ; Brodin, P. ; Canaan, S. ; Cavalier, J-F.
Bioorganic Chem 2018, 81, 414-424.

1-Ethyl-3-methylimidazolium tartrate chiral ionic liquids : preparation, characterization and opportunities thereof
Castellan, T. ; Cuyamendous, C. ; Fitremann, J. ; Galano, J-M. ; Oger, C ; Durand,T. ; Guillen, F. ; Génisson, Y.
New J Chem 2018, 42, 18739-18748.

Structural/functional matches and divergences of phytoprostanes and phytofurans with bioactive human oxylipins
S. Medina, Á. Gil-Izquierdo, T. Durand, F. Ferreres, R. Domínguez-Perles
Antioxidants, 2018, 7, 165.


Validated analytical method to determine new salivary lipid peroxidation compounds as potential neurodegenerative biomarkers
A. Garcia-Blanco, P. Carrascosa, C. Oger, C. Vigor, J-M. Galano, T. Durand, M. Baquero, M. Vento, C. Chafer-Pericas
J Pharm Biomed Anal 2019, 164, 742-749.

Statement of foliar fertilization impact on yield, composition, and oxidative biomarkers in rice.
Pinciroli, M., Domínguez-Perles, R., Garbi, M., Abellán, A., Bultel-Poncé V.,Durand. T., Galano, J.M., Ferreres, F., Gil-Izquierdo, A.
J Agric Food Chem2019, 67, 597-605.

Comparative study of different cocoa (Theobroma cacao L.) clones in terms of their Phytoprostanes and Phytofurans contents.
León-Pérez, D. ; Collado-González, J. ; Medina, S. ; Cano-Lamadrid, M. ; Durand, T. ; Guy, A. ; Galano,
J.-M. ; Carbonell-Barrachina, A. ; Londoño-Londoño, J. ; Ferreres, F. ; Gil-Izquierdo, A.
Food Chem 2019, 280, 231-239.

Obesogenic diet in aging mice alters gut microbe composition and disruption of neutrophil:lymphocyte ratiopromoting acute heart failure
V. Kain, P. Eipers, W. Van Der Pol, N. Mariappan, A. Ahmed, C. Morrow, D. L. Gibson, C. Gladine, C. Vigor, T. Durand, G. V. Halade
FASEB J 2019, 33, 6456-6469.

Potential of Physalis peruviana calyces a low-cost valuable ressources of phytoprostanes and phenolic compounds.
S. Medina, J. Collado-Gonzáleza, F. Ferreresa, J Londoño-Londoño, C. Jiménez-Cartagenab, A. Guy, T. Durand, J-M Galano, A. Gil-Izquierdo
J. Sci. Food Agri. 2019, 99, 2194–2204.

Twenty-week follow-up of inflammation and oxidative stress during installation and progression of hepatic steatosis in high fat/high fructose diet-fed rats
C. Feillet-Coudray, G. Fouret, C. Vigor, B. Bonafos, A. Blachnio-Zabielska, J. Rieusset, T. Durand, F. Casas, S. Gaillet1, J-F. Landrier and C. Coudray
Lipids 2019, 54, 81-97.

Lipid mediators from Timothy grass pollen contribute to the effector phase of allergy and prime dentritic cells for glycerolipid presentation
Gonzalez Roldan, N ; Engel, R. ; Düpow, S. ; Jakob, K. ; Koops, F. ; Orinska, Z. ; Vigor, C. ; Galano, J-M. ; Durand, T. ; Jappe, U. ; Duda, K. A.
Frontiers in Immunol. 2019,10, 974

Identification and quantification of phytoprostanes, and phytofurans, of coffee and cocoa by- and co-products
M. Ruesgas-Ramon, M. C. Figueroa-Espinoza, E. Durand, M. L. Suarez Quiroz, O. Gonzales Rios, A. Rocher, G. Réversat, J. Vercauteren, C. Oger, J-M. Galano, T. Durand, C. Vigor
Food Funct 2019, 10, 6882-6891.

Assesment of lipid peroxidation and articifial neural network models in early Alzheimer Disease diagnosis
C. Pena-Bautista, C. Oger, T. Durand, M. Baquero, M. Vento, C. Chafer-Pericas
Clin Biochem. 2019, 72, 64-70.

176 - Development of an optimized LC-MS method for the detection of specialized pro-resolving mediators in biological samples
Kutzner, L. ; Rund, K. ; Ostermann, A. ; Hartung, N. ; Galano, J-M. ; Balas, L. ; Durand, T., : Balzer, M. ; David, S. ; Schebb, N. H.
Front Pharmacol 2019, 10, 169.

Formation of trans-epoxy fatty acids correlates with formation of isoprostanes and could serve as biomarker of oxidative stress
Rund, K. ; Wecklein, S. ; Heylmann, D. ; Seiwert, N. ; Oger, C. ; Galano, J-M. ; Durand, T. ; Chen, R. ; Gueler, F. ; Fahrer, J. ; Borhorst, J. ; Schebb, N. H.
Prost Other Lipid Med 2019, 144, 106334.

Protectin D1 is rapidly metabolized by β-oxidation of its polar head chain
Balas, L. ; Risé, P. ; Gandrath, D. ; Rovati, G. E. ; Bolego, C. ; Stellari, F. ; Trenti, A. ; Buccellati, C. ; Durand, T. ; Sala, A.
J Med Chem 2019, 62, 9961-9975.

The value of legume foods as dietary source of phytoprostanes and phytofurans is depedant on species, varriety and growing conditions.
M. C. Garcia-Garcia, M del Rio Celestino, C. Egea-Gilabert, A. Gil-Izquerdo, J-M. Galano, T. Durand, C. Oger, J. A. Fernandez, Frederico Ferreres, R. Dominguez-Perles
Eur J Lipid Sci Techn 2019, 121, 1800484.

Aged black garlic has stronger antioxidant potency than white garlic in mild hypercholesterolemia patients
H H Leung, Y F Yau, Y Y Lee, C Oger, T Durand, J-M Galano, W M Loke and J C-Y Lee
Eur J Lipid Sci Tech 2019,121, 1900069.

Phenolic, oxylipin and fatty acid profiles of the Chilean hazelnut (Gevuina avellana) : antioxidant activity and inhibition of pro-inflammatory and metabolic syndrome associated enzymes
L. L. Pino ; F. Jimenez-Aspee ; C. Theoduloz ; A. Burgos-Edwards ; R. Dominguez-Perles ; C. Oger ; T. Durand ; A/ Gil-Izquierdo ; L. Bustamante ; C. Mardones ; K. Marquez ; D. Contreas ; G. Schmeda-Hirschmann
Food Chem, 2019, 298, 125026.

Increased isoprostanoid levels in brain from murine model of Krabbe disease – relevance of isoprostanes, dihomo-isoprostanes and neuroprostanes to disease severity.
C. Signorini, V. Cardile, G. Pannuzzo, A. C. E. Graziano, T. Durand, J-M. Galano, C. Oger, S. Leoncini, A. Cortelazzo, J. C-Y. Lee, J. Hayek, C. De Felice.
Free Radic Biol Med 2019, 139, 46-54.

Limited antioxidant effect of rosemary in lipid oxidation of pan-fried salmon
K. S. Leung, H. H. Leung, C. Y. Wu, J-M. Galano, T Durand, J. C-Y Lee
Biomolecules 2019, 9, 313.

Increase in oxidation of omega-6 and decrease in omega-3 polyunsaturated fatty acid elevates the risk of exudative AMD development in Chinese adults
H. H. Leung, A. LK Ng, T Durand, R. Kawasaki, C. Oger, L. Balas, J-M Galano, I. YH Wong and J. C-Y Lee
Free Radic Biol Med 2019, 145, 349-356.

Short-chain lipid peroxidation products form covalent adducts with pyruvate kinase and inhibit its activity in vitro and in breast cancer cells.
C. C. Sousa, A. Ahmed, W. L. Dann, J. Asman, T. Durand, A. Guy, A. R. Pitt, C. M. Spickett
Free Radic Biol Med 2019, 144, 223-233.

Bis-allylic deuterated DHA alleviates oxidative stress in retinal epithelial cell : promising application for oxidative stress driven diseases.
M. Rosell, M. Giera, P. Brabet, M. Schephinov, M. Guichardant, T. Durand, J. Vercauteren, J-M. Galano, C. Crauste
Antioxidants 2019, 8, 447.

Evaluation of amidoxime derivatives as prodrug candidates of potent bis-cationic antimalarials
O. Berger, S. Ortial, S. Wein, S. Denoyelle, F. Bressolle, T. Durand, R. Escale,H. Vial and Y. Vo-Hoang
Bioorg Med Chem Lett 2019, 29, 2203-2207.

Multiplex profiling of inflammation-related bioactive lipid mediators in Toxocara canis- and T. cati-induced neurotoxocarosis in mice
P. Waindok, E. Janecek-Erfurth, D. Lindenwald, E. Wilk, K. Schughart, R. Geffers, L. Balas, T. Durand, K. M. Rund, N. Helge Schebb, C. Strube
PLOS-NTB 2019, 13(9), e0007706

Effect of Dietary n-3 Source on Rabbit Male Reproduction
C. Castellini, S. Mattioli, C. Signorini, E. Cotozzolo, D. Noto, E. Moretti, G. Brecchia, A. Dal Bosco, G. Belmonte, T. Durand,C. De Felice, G. Collodel
Oxid Med Cell Long 2019, 3279670

Does Pasteurized Donor Human Milk Efficiently Protect Preterm Infants Against Oxidative Stress ?
A Parra-Llorca, M Gormaz, Á Sánchez-Illana, J D Piñeiro-Ramos, M C Collado, E Serna, M Cernada, A Nuñez-Ramiro, A Ramón-Beltrán, C Oger, J-M Galano, C Vigor, T Durand, J Kuligowski, and M Vento
Antiox Redox Sign 2019, 31, 791-799.

Non-invasive assessment of oxidative stress in preterm infants
C. Peña-Bautista, T Durand, C. Vigor, C. Oger, J-M Galano, C. Cháfer-Pericás
Free Radic Biol Med 2019, 142, 73-81

Limited antioxidant effect of rosemary in lipid oxidation of pan-fried salmon
K. S. Leung, H. H. Leung, C. Y. Wu, J-M. Galano, T Durand, J. C-Y Lee
Biomolecules 2019, 9, 313.

Increase in oxidation of omega-6 and decrease in omega-3 polyunsaturated fatty acid elevates the risk of exudative AMD development in Chinese adults
H. H. Leung, A. LK Ng, T Durand, R. Kawasaki, C. Oger, L. Balas, J-M Galano, I. YH Wong and J. C-Y Lee
Free Radic Biol Med 2019, 145, 349-356.

New screening approach for Alzheimer’s disease risk assessment from urine lipid peroxidation compounds
C. Peña-Bautista, C. Vigor, J-M. Galano, C. Oger, T. Durand, I. Ferrer Cairols, A. Cuevas, R. López-Cuevas, M. Baquero, M. López-Nogueroles, M. Vento, D. Hervás-Marín, A. García-Blanco, and C. Chafer-Pericas
Sci Reports 2019, 9, 14244.


Lipokine 5-PAHSA is Regulated by Adipose Triglyceride Lipase and Primes Adipocytes for de novo Lipogenesis in Mice
V. Paluchova, M. Oseeva, M. Brezinova, T. Cajka, K. Bardova, K. Adamcova, P. Zacek, L. Balas, H. Chodounska, E. Kudova, T. Durand, M. Rossmeisl, N. Abumrad, J. Kopecky, O. Kuda
Diabetes 2020, 69, 300-312.

Oxidized products of alpha-linolenic acid negatively regulate cellular survval and motility of breast cancer cells
Gutierrez, J.L. ; Ben Hasssen, C. ; Oger, C. ; Galano, J-M. ; Durand, T. ; Frank, P.G.
Biomolecules, 2020, 10, 50

Dietary omega-3 PUFA improved tubular function after ischemia induced acute kidney injury in mice but did not attenuate impairment of renal function
K. Rund, S. Peng, R. Greite, C. Claaßen, F. Nolte, C. Oger, J-M. Galano, L. Balas, T. Durand, R. Chen, F. Gueler, N. H. Helge Schebb
Prost Other Lipid Med 2020, 146, 106386.

Brain protein changes in Mecp2 mouse mutant models : effect on disease progression of Mecp2 brain specific gene reactivation
A Cortelazzo, C. De Felice, J. Guy, A. M. Timperio, L. Zolla, R. Guerranti, S. Leoncini, C. Sigorini, T. Durand, J. Hayek
J Proteomics, 2020,210, 103537.

Urinary oxilipin signature as biomarkers to monitor the allograft function during the first six months post-renal transplantation by lipidomic approach
S. Medina, I. De las Heras-Gómez, T. Casas-Pina, V. Bultel-Poncé, J-M. Galano, T. Durand, P. Martínez-Hernández, F. Ferreres, L. Jimeno, S. Llorente, A. Gil-Izquierdo
Free Radic Biol Med 2020, 146, 340-349.

Optimization of free phytoprostanes and phytofurans production by enzymatic hydrolysis of pea extracts using bacterial esterases
R. Domínguez-Perles, I. Sánchez-Martínez, M. Dolores Rodríguez-Hernández, I. López, C. Oger, A. Guy, T. Durand, J-M. Galano, F. Ferreres, Á. Gil-Izquierdo
J Agric Food Chem 2020, 68, 3445-3455.

Long-term dietary intake of 9-PAHPA or 9-OAHPA increases basal metabolism and insulin sensitivity but disrupts liver homeostasis in healthy mice
M. Benlebna, L. Balas, B. Bonafos, L. Pessemesse, C. Vigor, J. Grober, F. Bernex, G. Fouret, S. Gaillet, Dr J-F. Landrier, O. Kuda, T. Durand, C. Coudray, F. Casas, C. Coudray
J Nutr Biochem 2020, 79, 108361.

Combination of lutein and zeaxanthin with DHA increased the protection of ROS-stressed retinal cells
H. H. Leung, J-M Galano, C. Crauste, T. Durand, and J. C-Y Lee
Neurochem Res 2020, 45, 1007-1019

203 - Non-enzymatic oxygenated metabolite of docosahexaenoic acid, 4(RS)-4-F4t-neuroprostane, act as bioactive lipid molecule in neuronal cell
Y.Y. Lee, J-M. Galano, H. H. Leung, Laurence Balas, C. Oger, T. Durand, and J. C-Y. Lee
FEBS Letters 2020, 594, 1797-1808

Lipophenol protects against retinal degeneration in mouse model of Stargardt’s disease by targeting retinaldehyde toxicity.
A. Cubizolle, D. Cia, N. Pinquier, L. Guillou, N. Jacquemot, M. Rosell, C. Angebault-Prouteau, G. Lenaers, T. Durand, C. P. Hamel, J. Vercauteren, C. Crausteand P. Brabet
J Cell Mol Med 2020, 24, 5057-5069

Pro-regenerative protectin D1 controls immune cell function during regeneration
M. Nguyen-Chi, P. Luz-Crawford, L. Balas, T. Spika, R. Contreas, A. Barthelaix, G. Lutfalla, T. Durand, C. Jorgensen, F. Djouad
Br J Pharmacol 2020,177, 4055-4073.

Clinical utility of lipid peroxidation biomarkers in plasma for Alzheimer Disease differential diagnosis
C. Peña-Bautista,T. Durand, C. Vigor, A. Cuevas, M. Baquero, M. Vento, D. Hervas-Marin, C. Chafer-Pericas
Antioxidants 2020, 9, 649

Dissecting the antibacterial activity of Oxadiazolone-core derivatives against Mycobacterium abscessus
A. Madani, I. Mallick, A. Guy, C. Crauste, T. Durand, P. Fourquet, S. Audebert, L. Camoin, S. Canaan and J-F. Cavalier
PlosOne 2020, 15, e0238178.

Preclinical pharmacology of a lipophenol in mouse model of light-induced retinopathies
N. Taveau, A. Cubizolle, L. Guillou, N. Pinquier, E. Moine, D. Cia, J. Vercauteren, T. Durand, C. Crauste, P. Brabet
Exp Mol Med2020, 52, 1090-1101.

Characterization and modulation of brain lipids content of raibow trout fed with 100% plant based diet rich in omega-3 long chain polyunstaurated fatty acids DHA and EPA
J Roy, C. Vigor, G Reversat, B. Zhou, J Vercauteren, A. Surget, L. Larroquet, G. Corraze, A. Lanuque, F. Sandres, F. Terrier, C. Oger, J-M. Galano, T. Durand
Biochimie, 2020, 178, 137-147.

Oxylipin regulation by phenolic compounds from coffee beverage : Positive outcomesfrom a randomized controlled trial in healthy adults and macrophage derived foamcells.
O. J. Lara-Guzman, S. Medina, L. R. Alvarez, C. Oger, T. Durand, J-M. Galano, N. Zuluaga, A. Gil-Izquierdo, K. Munoz-Durango,
Free Rad Biol Med 2020, 160, 604-617.

Oxidative stress and antioxidant response in rainbow trout fry exposed to acute hypoxia is affected by selenium nutrition of parents and during first exogenous feeding.
P. Wischhusen, L. Larroquet, T. Durand, C. Vigor, P. Antony J. Prabhu, V. Véron, M. Briens, S. J. Kaushik, B. Fauconneau, S. Fontagné-Dicharry
Free Radical Biol Med 2020, 155, 99-113.

Bioavailable phytoprostanes and phytofurans from Gracilaria longissima have anti-inflammatory effects in endothelial cells
Martinez. Sánchez, S., Domínguez-Perles, R., Montoro-García, S., Gabaldón Hernández J.A., Guy, A., Durand, T.,Oger, C., Ferreres, F., Gil-Izquierdo, A.
Food Funct 2020, 11, 5166-5178

Bioactive plant oxylipins-based lipidomics in eighty worldwide commercial dark chocolates : Effect of cocoa and fatty acid composition on their dietary burden.
D. León-Perez, R. Domínguez-Perles, J. Collado-González, M. Cano-Lamadrid, T. Durand, A. Guy, J-M. Galano, Á. Carbonell-Barrachina, J. Londoño-Londoño, F. Ferreres, C. Jiménez-Cartagena, Á. Gil-Izquierdo, S. Medina
Microchem J 2020, 157, 105083

First total syntheses of novel non-enzymatic polyunsaturated fatty acid metabolites and their identification in edible oils
T. Pavlíčková, V. Bultel-Poncé, A. Guy, A. Rocher, G. Reversat, C. Vigor, T. Durand, J-M. Galano, U. Jahn and C. Oger
Chemistry Eur J 2020,29, 10090-10098.

Total synthesis of a Docosahexaenoic Acid Prostanoid Using an Intramolecular Organocatalytic Michael Reaction of a Formyl-Enal Derivative
J. Revol-Cavalier, V. Bultel-Poncé, A. Guy, T. Durand, C. Oger, and J-M. Galano
Org Lett 2020, 22, 7455-7459.

Lactobacillus rhamnosus GG and oat beta-glucan regulated fatty acid profiles along the
gut-liver-brain axis of mice fed with high fat diet and demonstrated antioxidant and
anti-inflammatory potentials
Y. F. Yau, H. El-Nezami, J-M. Galano, Z. M. Kundi, T.Durand, J. C-Y. Lee
Mol Nutr Food Res 2020, 64, 2000566.

Phytoprostanes and phytofurans –oxidative stress and bioactive compounds– in almonds are affected by deficit irrigation in almond trees.
Lipán, L. ; Collado, J. ; Dominguez-Perles, R. ; Corell, M. ; Bultel-Poncé, V. ; Galano, J-M. ; Durand, T. ; Medina, S. ; Gil-Izquierdo, A. ; Carbonell-Barrachina, Á.
J Agric Food Chem 2020, 68, 7214-7225.

Targeted lipidomics profiling reveals the generation of hydroxytyrosol-fatty acids in hydroxytyrosol-fortified oily matrices : new analytical methodology and cytotoxicity evaluation.
Medina, S. ; Dominguez-Perles, R. ; Auñon, D. ; Moine, E. ; Durand, T. ; Crauste, C. ; Ferreres, F. ; Gil-Izquierdo, A
J Agric Food Chem 2020, 68, 7789-7799.

Effects of deficit irrigation, rootstock and toasting on the contents of fatty acids, phytoprostanes, and phytofuranes in pistachios
J. Collado-González, M. Cano-Lamadrid, Á. A. Carbonell-Barrachina, S. Medina, A. Torrecillas, A. Guy, J-M. Galano, T. Durand, F. Ferreres, Á. Gil-Izquierdo
J Agric Food Chem 2020, 68, 8915-8924.

Evaluation of Phoenix dactylifera edible parts and byproducts as sources of phytoprostanes and phytofurans
S. Medina, Á. Gil-Izquierdo, I. M. Abu-Reidah, T. Durand, V. Bultel-Poncé, J-M. Galano, R. Domínguez-Perles
J Agric Food Chem 2020,68, 8942-8950.

Isoprostanoid profiling of marine microalgae
C. Vigor, C. Oger, G. Reversat, A. Rocher, B. Zhou, A. Linares-maurizi, A. Guy, V.
Bultel-Poncé, J-M. Galano, J. Vercauteren, T. Durand, P. Potin, T. Tonon, C. Leblanc
Biomolecules, 2020, 9, 649.

Measurement of enzymatic and non-enzymatic polyunsaturated fatty acid oxidation products in plasma and urine of macular degeneration using LC-QTOF-MS/MS
H. H. Leung, K. S. Leung, T. Durand, J-M. Galano and J. C-Y. Lee
Lipids, 2020, 55, 693-706.

Update on LIPID MAPS Classification, Nomenclature and Shorthand Notation for MS-derived Lipid Structures
G. Liebisch, E. Fahy, J. Aoki, E. A. Dennis, T. Durand, C. S. Ejsing, M. Fedorova, I. Feussner, W. J. Griffiths, H. Köfeler, A. H. Merrill Jr., R. C. Murphy, V. B. O’Donnell, O. Oskolkova, S. Subramaniam, M. J. O. Wakelam, F. Spener
J Lipid Res 2020, 61, 1539-1555.

Chemical Changes in Over-Oxidized Fish Oils
A. S. Phung, G. Bannenberg, C. Vigor, G. Réversat, C. Oger, M. Roumain, J-M. Galano, T. Durand, G. G. Muccioli, A. Ismail, S. C. Wang
Foods 2020, 9, 1501.

Long chain omega-3 fatty acids and their oxidized metabolites are associated with reduced prostate tumor growth
N. Gevariya, A. Bergeron, K.Robitaille, M. Besançon, V. Picard, C. Oger, J-M. Galano, T. Durand, Y. Fradet, P. Julien, J-F. Bilodeau, V. Fradet
Prostagl. Leuko. Ess. Fatty Acids 2020, 164, 102215.

FAHFAs regulate mitochondrial respiratory chain activity and proliferation of C2C12 myoblasts
M. Benlebna, L. Balas, L. Pessemesse, B. Bonafos, G. Fouret, L. Pavlin, B. Goustard, S. Gaillet, T. Durand, C. Coudray,C. Feillet-Coudray and F. Casas
Int J Mol Sci 2020, 21, 9046.


Enrichment of alpha-linolenic acid in rodent diet reduced oxidative stress and inflammation during myocardial infarction
K. S. Leung, J-M. Galano, C. Oger, T. Durand, J. C-Y. Lee
Free Radical Biol Med 2021, 162, 53-64.

Distinct roles of adipose triglyceride lipase and hormone-sensitive lipase in the catabolism of triacylglycerol estolides
Brejchova, K. Radner, F. ; Balas, L. ; Paluchova, V. ; Cajka, Tomas ; C., Hana ; K., E. ; Schreiber, R. ; Durand, T. ; Zechner , R. ; Kuda, O.
PNAS 2021, 118, e2020999118.

New lipophenols prevent carbonyl and oxidative stresses involved in macular degeneration.
Moine, E. ; Boukhallat , M. ; Cia, D. ; Jacquemot, N. ; Guillou, L. ; Durand, T. ; Vercauteren, J. ; Brabet, P. ; Crauste, C.
Free Radic Biol Med 2021, 162, 367-382.

Luminescence imaging of leaf damage induced by lipid peroxidation products and its modulation by β-cyclocitral
Rac, M. ; Shumbe. L. ; Oger, C. ; Guy, A. ; Vigor, C. ; Ksas, B. ; Durand, T. ; Havaux, M.
Physiol Planet 2021, 171, 246-259.

Long-term intake 9-PAHPA or 9-OAHPA modulates favorably the basal metabolism and exerts an insulin sensitizing effect in obesogenic diet-fed mice
M. Benlebna ; L. Balas ; B. Bonafos ; L. Pessemesse ; G. Fouret ; C. Vigor ; J. Grober ; S. Gaillet ; F. Bernex ; J-F. Landrier ; O. Kuda ; T. Durand ; C. Coudray ; F. Casas ; C. Feillet-Coudray
Eur J Nutr 2021, 60, 2013-2027.

Walnut-enriched diet elevated α-linolenic acid, phytoprostanes and phytofurans in rat liver and heart tissues, and modulated anti-inflammatory lipid mediators in the liver
K. S. Leung, J-M. Galano, C. Oger, T. Durand, J. C-Y Lee
J Agric Food Chem 2021, 69, 9094-9101.

Revisiting Brassica napus (rapeseeds) phytochemicals nutritional interest in the metabolically impaired ob-mouse using a multi-scale omics approach
D. Bennouna, F. Tourniaire, T. Durand, J-M. Galano, F. Fine, K. Fraser, S. Bennatia, C. Rosique, C. Pau, C. Couturier, C. Pontet, C. Vigor, J-F. Landrier, J-C. Martin
Food Chem Mol Sci 2021, 2, 10011

Analysis of lipid peroxidation by UPLC-MS/MS and retinoprotective effects of the natural polyphenol pterostilbene
I. Torres-Cuevas, I. Millán, M. Asensi, M. Vento, C Oger, J-M. Galano, T. Durand, Á. L. Ortega
Antioxidants 2021, 10, 168

Peripancreatic Adipose Tissue Remodeling and Inflammation during High Fat Intake of Palm Oils or Lard in Rats
J. Laget,Y. F. Djohan, L. Jeanson, K. Muyor, E. Badia,J-P Cristol, C. Coudray, C. Feillet-Coudray, C. Vigor, C. Oger, J-M. Galano, T. Durand, A-D. Lajoix, N. Gayrard, B. Jover
Nutrients, 2021, 13(4), 1134

Phytoprostanes and phytofurans modulate COX-2-linked inflammation markers in LPS-stimulated THP-1 monocytes by lipidomics workflow
M. Campillo, S. Medina, F. Fanti, J. I. Gallego-Gomez, A. Simonelli-Munoz, V. Bultel-Poncé, T. Durand, J-M. Galano, F. A. Tomas-Barberan, Á. Gil-Izquierdo, R. Domínguez-Perles,
Free Radic Biol Med 2021, 167, 335-347.

Circulating 4-F4t-neuroprostane and 10-F4t-neuroprostane are related to MECP2 gene mutation and natural history in Rett syndrome
C. De Felice, C. Signorini, S. Leoncini, T. Durand, J-M. Galano, A. Guy, V. Bultel-Poncé, C. Oger, J. C-Y. Lee, L. Ciccoli and J. Hayek
Int J Mol Sci 2021, 22, 4240.

Effect of coffee and cocoa-based confectionery containing coffee on markers of DNA damage and lipid peroxidation products : results from the Pocket-4-Life project
D. Martini, R. Domínguez-Perles, A. Rosi, M. Tassotti, D. Angelino, S. Medina, A. Guy, C. Oger, L. Gigliotti, T. Durand, M. Marino, H. Gottfried-Genieser, M. Porrini, M. Antonini, A. Dei Cas, R. Bonadonna, F. Ferreres, F. Scazzina, F. Brighenti, P. Riso, C. Del Bo, P. Mena, A. Gil-Izquierdo, and D. Del Rio
Nutrients, 2021, 13, 2399.

First total synthesis of phytoprostanes with prostaglandin-like configuration, evidence for their formation in edible vegetable oils and orienting study of their biological activity
J. Smrček, M. Hájek, O. Hodek, K. Čížek, R. Pohl, E. Jahn, J-M. Galano, C. Oger, T. Durand, J. Cvačkaand U. Jahn
Chem Eur J. 2021, 27, 9556-9562.

Hydroxytyrosol and its lipophenolic derivatives modulate the quantitative isoprostanoid profile of THP-1 monocytes under pro-oxidant conditions
C. Alemán-Jimenez ; R. Domínguez-Perles ; F. Fanti ;J. I. Gallego- Gómez, A. Simonelli-Muñoz, E. Moine, T. Durand ; C. Crauste ; Á. Gil-Izquierdo, S. Medina
Microchem J 2021,170, 106703.

Lipid peroxidation assessment in preclinical Alzheimer Disease diagnosis
C. Peña-Bautista, L. Álvarez-Sánchez, I. Ferrer, M. López-Nogueroles, A. José Cañada-Martínez, C. Oger,
J-M Galano, T. Durand, M. Baquero, C. Cháfer-Pericás
Antioxidants 2021, 10, 1043.

F4-neuroprostanes : a role in sperm capacitation
C. Signorini, E. Moretti, D. Noto, S. Mattioli, C. Castellini, N. A. Pascarelli, T. Durand, C. Oger, J-M. Galano, C. De Felice, J. L. C. Lee, G. Collodel
Life 2021, 11, 655.

Oxidized phospholipids on alkyl-amide scaffold demonstrate anti-endotoxin and endothelial barrier-protective properties
O. Oskolkova, A. Hodzic, B. Gesslbauer, D. C. Hofer, J. G. Bogner-Strauss, J-M. Galano, C. Oger, A. Birukova, T. Durand, K. Birukov and V. Bochkov
Free Radic Biol Med 2021, 174, 264-271.

Decreased Fatty Acid Transporter FABP1 and Increased Isoprostanes and Neuroprostanes in the Human Term Placenta : Implications for Inflammation and Birth Weight in Maternal Pre-Gestational Obesity
L. Belcastro, C. S. Ferreira, M. A. Saraiva, D. B. Mucci, A. Murgia, C. Lai, C. Vigor, C. Oger, J-M. Galano, G. D. A. Pinto, J. L. Griffin, A. G. Torres, T. Durand, G. J. Burton, F. L. C. Sardinha, and T. El-Bacha
Nutrients 2021, 13, 2768.

Do levels of lipid peroxidation biomarkers reflect the degree of brain injury in newborns ?
M. M. Cascant-Vilaplana, Á. Sánchez-Illana, J. David Piñeiro-Ramos, R. Llorens-Salvador, G. Quintás, C. Oger, J-M. Galano, C. Vigor, T. Durand,J. Kuligowski, M. Vento, and the HYPOTOP Study Group
Antioxidant and Redox Signaling 2021, 37, 1467-1475.

Phytoprostanes from date palm fruit and by-products : five different varieties grown in two different locations as potential sources.
Ahmed, O. S. ; Sedraoui, S ; Zhou, B ; Reversat, G. ; Rocher, A. ; Bultel-Ponce, V. ; Guy, A. ; Vercauteren, J. ; Selim, S. ; Galano, J-M. ; Durand, T. ; Oger, C. ; Vigor, C.
J Agric Food Chem 2021, 69, 13754-13761.

Fatty acid hydroxytyrosol esters of olive oils are bioaccessible according to stimulated in vitro gastrointestinal digestion : Unravelling the role of digestive enzymes on their stability.
B. Alemian-Jimenez ; R. Dominguez-Perles, J. I. Gallego-Gomez ; A. Simonelli-Muñoz ; E. Moine ; T. Durand ; C. Crauste ; F. Ferreres, A. Gil-Izquierdo, S. Medina
J Agric Food Chem 2021, 69,14165-14175.


-linolenic acid and product octadecanoids in Styrian pumpkin seeds and oils : How processing impacts Lipidome on fatty acid, triglyceryde and oxylipin molecular structures.
C. Vigor, T. Zullig, T. O. Eichmann, C. Oger ; B. Zhou, G. N. Rechberger, L. Hilsberg, M. Trotzmuller, H. Wolinski, J-M. Galano, T. Durand, F. Spenner,
Food Chem 2022, 371, 131194.

Isoprostanoid plasma levels are relevant to cerebral adrenoleukodystrophy disease
C. Signorini, C. De Felice, T. Durand, J-M. Galano, C. Oger, S. Leoncini, L. Basso, J. Hayek, J. C-Y. Lee, T. C. Lund ; P. L. Orchard
Life 2022, 12, 146.

Discovery and quantification of lipoamino acids in bacteria
A. Hueber ; C. Petitfils ; P. Le Faouder ; G. Langevin ; A. Guy ; J-M. Galano ; T. Durand ; J-F. Martin ; J-C. Tabet ; N. Cenac, J Bertand-Michel
Anal Chim Acta 2022, 1193, 339316.

Plasma oxylipin levels may predict Covid-19 patient outcomes. An observational and retrospective study.
D. Biagini, M. Franzini, P. Oliveri, T. Lomonaco, S. Ghimenti, A. Bonini, F. Vivaldi, L. Macera, L. Balas, T. Durand, C Oger, J-M. Galano, F. Maggi, A. Celi, A. Paolicchi, F. Di Francesco
Free Radic Biol Med 2022, 180, 236-243.

Identification of bacterial lipo-amino acids : origin of regenerated fatty acid carboxylate from dissociation of lipo
glutamate anion
A. Hueber ; Y. Gimbert ; G Langevin, J-M. Galano ; A. Guy ; T. Durand ; N. Cenac ; J. Bertrand-Michel ; J-C. Tabet
Amino Acids 2022, 54, 241-250.

Total Synthesis of DHA and DPAn-3 non-enzymatic oxylipins
A. Guy, J. Mérad, T. Degrand, G. Reversat, V. Bultel-Poncé, T Durand, J-M. Galano, C. Oger
Synthesis 2022, 24,1431-1446.

Linotrins : omega-3 oxylipins featuring an E,Z,E conjugated trien motif are present in the plant kingdom and alleviate inflammation in LPS-challeged microglial cells.
L. Balas ; S. Dey, S. Bérauld-Dufour ; D. E. Riechers ; O. Landau ; J. Bertand-Michel ; T. Durand ; N. Blondeau
Eur J Med Chem 2022, 231, 114157.

Analysis of fatty acid esters of hydroxy fatty acids in fermented brown rice and rice bran
A. Watabnabe, H. Yamaguchi, D. Saigusa, J. Ogura, L. Balas, T. Durand, N. Mano
Food Chem Adv, 2022, 1, 100040.

Triacylglycerols containing branched palmitic acid ester of hydroxystearic acid (PAHSA) are hydrolyzed by carboxyl ester lipase in the breast milk
K. Brejchova, V. Paluchova, M. Brezinova, T. Cajka, L. Balas, T. Durand, M. Cerna/Krizova, Z. Stranak, O. Kuda
Food Chem 2022, 388, 132983

Identification and quantification of phytoprostanes and phytofurans in Acacia Cyanophylla Lindl Seed
M. Mersni, B. Zhou, G. Reversat, I. Yangui, M. Larbi Khouja, A. Guy, C. Oger, J-M. Galano, T. Durand, C. Messaoud, C. Vigor
Food Chem Adv 2022, 1, 100077
A dynamic Model for Estimating the interaction of ROS-PUFA-Antioxidants in Rabbit
Mattioli, S ; Dimauro, C ; Cesarani, A ; Dal Bosco, A ; Bartolini, D ; Galli, F ; Migni, A ; Sebastiani, B ; Signorini, C ; Oger, C ; Collodel, G ; Castellini, C
Antioxidan,ts 2022, 11, 535.

Reduced production of isoprostanes by the peri-pancreatic adipose tissue from Zucker fa/fa rats as a new mechanism for β-cell compensation in insulin resistance and obesity
J. Laget, C. Vigor, A. Rocher, J. Leroy, A. Nouvel, G. Reversat, C. Oger, J-M. Galano, T. Durand, S. Péraldi-Roux, J. Azay-Milhau, A-D. Lajoix
Free Radic Biol Med 2022, 182, 160-170.

259 – Straightforward syntheses of phytoprostanes and dihomo-phytoprostanes – non-enzymatic metabolites of g-linolenic, dihomo-g-linolenic and stearidonic acids
P. Fischer ; V. Bultel-Ponce ; A. Guy ; I. Gonzales ; P. A. Conde ; J-M.Galano, T. Durand ; C. Oger
Eur J Org Chem 2022, 16, e202200085

Neuroprotective effects of DHA-derived peroxidation product 4(RS)-4-F4t-Neuroprostane on microglia
X. Geng, J-M. Galano, C. Oger, G. Y. Sun, T. Durand, J. C. Lee
Free Radic Biol Med 2022, 185,1-5

Intranasal administration of nanovectorized docosahexaenoic acid (DHA) improves cognitive functions in two complementary mouse models of Alzheimer’s disease
Ch. Zussy, J. Rijo, T. Urgin, L. Otaegui, C. Vigor, N. Acar, G. Canet, M. Vitalis, F. Morin, E. Planel, C. Oger, T. Durand, S. L. Rajshree, L. Givalois, P. V. Devarajan, C. Desrumaux
Antioxidants 2022, 11, 838

Development of a Chiral Supercritic Fluid Chromatography-Tandem Mass Spectrometry and Reversed-Phase Liquid Chromatography-Tandem Mass Spectrometry Platform for the Quantitative Metabolic Profiling of Octadecanoid Oxylipins
Quaranta, B. Zöhrer, J. Revol-Cavalier, K. Benkestok, L. Balas, C. Oger, G. Keyes, Å. M. Wheelock, T. Durand, J-M. Galano, C. E. Ramsden, M. Hamberg, C. E. Wheelock
Anal Chem 2022, 94, 14618-14626.

Hydroxytyrosol fatty acid esters as new markers for detecting extra virgin olive oil inadequate storage conditions and refined olive oil blends by UHPLC-QqQ-MS/MS
S. Medina, D. Auñón, J. Lehoux, T. Durand, C. Crauste, Á. Gil-Izquierdo
Microchem J2022, 181, 107656

Macrophages undergo a behavioural switch during wound healing in zebrafish
T. Sipka, S. Ah Park, R. Ozbilgic, L. Balas, T. Durand, K. Mikula, G. Lutfalla, M. Nguyen-Chi
Free Radic Biol Med 2022, 192, 200-212.

Dietary antioxidant intake is inversely associated with 2,3-dinor oxylipin metabolites, the major excreted oxylipins in overweight and obese subjects
Ó. J. Lara-Guzmán, D. A. Rivera, V. Corrales, L. Salazar-Jaramillo, Á. Gil-Izquierdo, S. Medina, C. Oger, T. Durand, J-M. Galano J. S. Escobar, K. Muñoz-Durango, and J. A. Sierra.
Free Radic Biol Med 2022, 190, 42-54

Formulation and Evaluation of SNEDDS Loaded with Original Lipophenol for the Oral Route to Prevent Dry AMD and Stragardt’s Disease
M. Vincent, L. Simon, P. Brabet, P. Legrand, C. Dorandeu, J. Lai Kee Him, T. Durand, C. Crauste and S. Begu
Pharmaceutics 2022, 14, 1029.

Neutral Loss Mass Spectral Data Enhances Molecular Similarity Analysis in METLIN
Aisporna, A ; Benton, HP ; Chen, A ; Derks, RJE ; Galano, JM ; Giera, M ; Siuzdak, G,
J Am Soc Mass Spectro 2022, 33, 530-534.

Anti-Inflammatory and Antioxidant Capacity of a Fruit and Vegetable-Based Nutraceutical Measured By Urinary Oxylipin Concentration in a Healthy Population : A Randomized, Dou-ble-Blind, Placebo-Controlled Clinical Trial
R. Arcusa, J. Á. Carrillo, B. Cerdá, T. Durand, Á. Gil-Izquierdo, S. Medina, J-M. Galano, D. Villaño Valencia, J. Marhuenda, P. Zafrilla
Antioxidants 2022, 11, 1342.

Acute and rapid response of balm and spearmint to saline reclaimed water in terms of water relations, hormones, amino acids and plant oxylipins.
M.J. Gómez-Bellot, B. Lorente, S. Medina, A. Gil-Izquierdo, T. Durand, J-M Galano, S. Bañón, M.F. Ortuño, M.J. Sánchez-Blanco
Plants 2022, 11, 3427.

The Role of Peroxiredoxin 6 in Biosynthesis of FAHFAs
V. Paluchova, T. Cajka, T. Durand, C. Vigor, C. Dodia, S. Chatterjee, A. B. Fisher, O. Kuda
Free Rad BiolMed 2022, 193, 787-794.


9-PAHPA long term intake in DIO and db/db mice ameliorates insulin sensitivity but has few effects on obesity and associated metabolic disorders
B. Bonafos, A. J. Cortés Espinar, L. Balas, L. Pessemesse, K. Lambert, M. Benlebna, S. Gaillet, F. Pelletier, P. Delobel, M. Mullero, C. Bertrand-Gaday, T. Durand, C. Coudray, F. Casas, C. Feillet-Coudray
J Nutr Biochem 2023, 112, 109216.

Neuroprostanes and Isoprostanes in the human term placenta are altered by gestational diabetes mellitus and maternal overweight and obesity.
C. S. Ferreira , G. D. A. Pinto, C. Vigor, V. A. Goes, D. Bauer, D. B. Mucci, L. Belcastro, M. A. Saraiva, C. Oger, J-M. Galano, F. L. C. Sardinha, A. G. Torres, T. Durand, G. J. Burton, and T. El-Bacha
PLEFA 2023, 189, 102529.

Effects of fatty acid metabolites on adipocytes britening : a role of thromboxane A2
C. Colson ; P-L. Batrow ; S. Dieckmann ; L. Contu ; C. H. Roux ; L. Balas ; C. Vigor ; B. Fournaux ; N. Gauthier ; N. Rochet ; N. Bernoud-Hubac ; T. Durand ; D. Langin ; M. Klingenspor ; Ez-Z. Amri
Cells 2023, 12, 446.

Decreased oxidative stress and altered urinary oxylipidome by intravenous omega-3 fatty acid emulsion in a randomized controlled trial of older subjects hospitalized for COVID-19.
S-C. Pawelzik, H. Arnardottir, P. Sarajlic, A. Mahdi, C. Vigor, J. Zurita, B. Zhou, J. Kolmert, J-M. Galano, D. Religa, T. Durand, C. E. Wheelock, M. Bäck,
Free Radic Biol Med 2023, 194, 308-315.

F4-Neuroprostanes effects on human sperm
E. Moretti, C. Signorini, D. Noto, R. Corsaro, L. Micheli, T. Durand, C. Oger, J-M. Galano, G. Collodel
Int J Mol Sci 2023, 24, 935.

A Phytoprostane from Gracilaria longissima Increases Platelet Activation, Platelet Adhesion to Leukocytes and Endothelial Cell Migration by Potential Binding to EP3 Prostaglandin Receptor
S. Montoro-García, S. Martínez-Sánchez, M. Carmena-Bargueño, H. Pérez-Sánchez, M. Campillo, C. Oger, J-M. Galano, T. Durand, Á. Gil-Izquierdo and J. Antonio Gabaldón
Int J Mol Sci 2023, 24, 2730.

Identification of bacterial lipopeptides as key players in prenatal stress-induced visceral pain
B. Petitfils, S. Maurel, G. Payros, A. Hueber, B. Agaiz, G. Gazzo, R. Marrocco, F. Auvray, G. Langevin, J-P. Motta, P. Floch, M. Tremblay-Franco, J-M. Galano, A. Guy, T.Durand, S. Lachambre, J. Bertrand Michel, A. Saoudi, E. Oswald, P. Poisbeau, G. Dietrich, M. Serino, P. le Faouder, N. Cenac
Gut, 2023, in press.

Rice Brain lipidome identifies novel phospholipids, glycerolipids, and oxylipins and role in lipid metabolism of hypercholesterolemic children
M. C. Barros Antos ; N. Barouh ; V. Lullien ; V. Micard ; P. Villeneuve ; B. Zhou ; C. Oger ; C. Vigor, T. Durand ; M. S. Larraz Ferreira ; C. Bourlie-Lacanal ; E. Ryan
Mol Nutr Food Res 2023, in press

Articles published in proceedings
Oxidative Damage of Polyunsatured Fatty Acid Plays a Key Role in the Pathogenesis and Progression of Krabbe Desease
Graziano, A. C. E. ; Signorini, C. ; Pannuzzo, G. ; Durand, T. ; Galano, J. M. ; Oger, C. ; Leoncini, S. ; Cortelazzo, A. ; Lee, J. C. Y. ; Hayek, J. ; De Felice, C. ; Cardile, V
Acta Physiol2019, 227, 94-95

Does DHA open TREK-1 channels or is it NEO-PUFAs ?
Bertaud, A. ; Salmeron, F. ; Oger, C. ; Galano, J-M. ; Vigor, C. ; Jopling, C. ; Durand, T. ; Le Guennec, J-Y. ; Moha ou Maati H. ; Demion, M.
Acta Physiol2019, 227, 35

Impact of DHA on the cardiac function and regeneration mechanisms in zebrafish
Salmeron, F. ; Moha Ou Maati, H. ; Durand, T. ; Faucherre, A. ; Rolland, L. ; Oger, C. ; Vigor, C. ; Galano, J-M. ; Le Guennec, J.-Y. ; Jopling, C. ; Demion, M.
Acta Physiol2019, 227, 44

Obesogenic diet in aging mice alters gut microbe composition and disruption of neutrophil:lymphocyte ratiopromoting acute heart failure
V. Kain, P. Eipers, W. Van Der Pol, N. Mariappan, A. ahmed, C. Morrow, D. L. Gibson, C. Gladine, C. Vigor, T. Durand, G. V. Halade
FASEB J 2019, 33, 693-6.

Lipophenols as new therapeutics toward retinal degeneration : in vitro and in vivo pharmacological studies
E. Moine ; N. Taveau ; M. Vincent ; L. Guillou ; S. Begu ; J. Vercauteren ; T. Durand ; C. Crauste ; P. Brabet
Invest Ophthalmol Vis Sci 2020, 61, 4939.

Monitoring of urinary oxidative stress biomarker levels in newborns with
Hypoxic-Ischemic Encephalopathy
M. M. Cascant-Vilaplana, Á. Sánchez-Illana, J. D. Piñeiro-Ramos, G. Quintá, C. Oger, J-M. Galano, C. Vigor, T. Durand, M. Vento, J. Kuligowski
Free Radic Biol Med 2020, 159, s115

Targeted lipidomics of docosanoids and isoprostanoids in the umbilical cord : impact of preeclempsia, mode of delivery and fetal sex.
J-F. Bilodeau ; K. Greffard ; J. Larose ; C. Oger, J-M. Galano ; T. Durand
Placenta, 2021, 112, e1-e89, PL6.
Chemical compositional Change in Over-Oxidized Fish oil
Bannenberg, G ; Phung, A ; Vigor, C ; Reversat, G ; Oger, C (Oger ; Roumain, M ; Galano, JM ; Durand, T ; Muccioli, G ; Ismail, A ; Wang, S
J Am Oil Chem Soc 2021, 98, 126-127.

4-F4-neuroprostane and Its Potent Biological Action in Cardiovascular Diseases.
Demion M. and Galano J-M. 
J Am Oil Chem Soc 2021, 98, 219.

Microalgae Isoprostanoids profiling : species choice and growing conditions impact
Galano J-M.
J Am Oil Chem Soc 2021, 98, 266.

Isoprosnoids quantitative profiling of mediterranean mussels
Galano J-M.
J Am Oil Chem Soc 2021, 98, 266.

Protectin D1, an endogenous bioactive omega-3 oxylipin, Difficult to detect in-vivo ... Why ?
Galano J-M.
J Am Oil Chem Soc 2021, 98, 267.

Mass spectrometry method to profile isoprostanes and neuroprostanes in brain tissue : a study in Alzheimer Disease
Dias, I ; Millic, I ; Oger, C ; Galano, JM ; Durand, T ; Devitt, A ; Griffiths, H
Free Radic Biol Med 2021, 177, S17-S17.

the wonders of isoprostanoids in biological system
Lee J. C. Y., Galano J-M., Durand T.
J Am Oil Chem Soc 2022, 99, 16-16

Reviews published in peer reviews
Biological activities of non-enzymatic oxygenated metabolites of polyunsaturated fatty acids (NEO-PUFAs) derived from EPA and DHA : New anti-arrhythmic compounds ?
J-M Galano, J Roy, T Durand, J CY Lee, JY Le Guennec, C Oger, M. Demion
Mol. Aspect Medicine 2018, 64, 164-168

50 – Les FAHFAS, une nouvelle classe de lipides endogènes bioactifs
M. Benlebna, L. Balas, F. Casas, S . Gaillet, C. Coudray, T. Durand, C Feillet-Coudray
Cahiers de Nutrition et de Diététicte, 2018, 53, 100-105

Branched FAHFAs, appealing beneficial endoendogenous fat against obesity and type-2 diabetes
L. Balas, C. Feillet-Coudray, T. Durand
Chem. Eur. J. 2018, 24, 9463-9476.

History of chemical routes towards cyclic non-enzymatic oxygenated metabolites of polyunsaturated fatty acids
C Oger, A. De la Torre, C. Cuyamendous, M. Candy, T. Durand, J-M. Galano
Synthesis 2018, 50, 3257-3280.

Isoprostanoids in Clinical and Experimental Neurological Disease Models
C. Signorini, C. De Felice, J-M. Galano, C. Oger, S. Leoncini, A. Cortalesso, L. Ciccoli, T. Durand, J. Hayek, J. C. Y. Lee
Antioxidants 2018, 7, 88

New lipophenol antioxidant to reduce oxidative damages in retina pigment epithelial cells
Moine, E. ; Brabet, P. ; Guillou, L. ; Durand, T. ; Vercauteren, J ; Crauste, C.
Antioxidants 2018, 7, 197

Lipid Peroxidation : Analysis and Applications in Biological Systems.
Lee JC, Durand T.
Antioxidants 2019, 8, 40.

Moving forward with isoprostanes, neuroprostanes and phytoprostanes – where are we know ? -
O. S. Ahmed ; J-M. Galano ; T. Pavlickova ; J. Révol-Cavalier ; C. Vigor ; J. C-Y. Lee ; C. Oger ; T. Durand
Essays Biochem.2020, 64, 463-484.

Understanding FAHFAs : From Structure to Metabolic Regulation
K. Brejchova, L. Balas, V. Paluchova, M. Brezinova, T. Durand, O. Kuda
Prog Lipid Res 2020, 79, 101053.

Lipolytic enzymes inhibitors : a new way for antibacterial drugs discovery
Cavalier, J-F. ; Spilling, C. ; Durand, T. ; Camoin, L. ; Canaan, S.
Eur J Med Chem 2021, 209, 112908.

Potential Health Effects of Branched fatty Acids Esters of Hydroxy Fatty Acids.
M. Belebna, L. Balas, S. Guillet, T. Durand, O. Kuda, C. Coudray, F. Casas, C. Feuillet-Coudray
Biochimie 2021, 118, 13-22.

Polyunsaturated fatty acids and Fatty acid-derived lipid mediators : Recent advances in the understanding of their biosynthesis, structure and functions
S.C. Dyall ; L. Balas ; N.G. Bazan ; J.T. Brenna ; N. Chiang ; J. Dalli ; T. Durand ; J-M. Galano ; C.N. Serhan ; A.Y. Taha
Prog lipid Res 2022, 86, 101165

Isoprostanoids, Isofuranoids and isoketals – From Synthesis to Lipidomics
C. Vigor ; L. Balas ; A. Guy ; V. Bultel-Poncé ; G. Reversat ; J-M. Galano ; T. Durand ; C. Oger
Eur J Org Chem 2022, 22, e202101523

Synthesis of fatty acid bioconjugates and related dervitaives
C. Crauste ; J-M. Galano ; A. Guy ; J. Lehoux ; T. Durand ; L. Balas
Eur J Org Chem 2022, 22, e202101502


New uses of lipophenolic compounds
Crauste, C. ; Vercauteren, J. ; Veas, F. ; Durand, T. ; Blondeau N.
EP17306560.8, November 10, 2017 ; WO/2019/092239 (2019).

Lipophenolic flavonoid derivatives useful to reduce carbonyl and oxidative stresses (COS)
Crauste, C. ; Moine, E. ; Brabet, P. ; Durand, T. ; Vercauteren, J.
EP18305957.5 July 13 2018 ; WO 2020/012003 (2020).

Lipopeptide compounds for use in treatment of visceral and somatic pain disorders
N. Cenac, J. Bertand-Michel, Tereza Perez-Berezo, T. Durand, J-M. Galano, J. Pujo, E Oswald, P. Martin, P. Le Faouder, A. Guy,
WO 2018197666, Nov 1, 2018

Methods and Pharmaceutical Composition for the Treatment of Disorders or Diseases asscociated with Ryanodine Receptor Dysfunction
A. Lacampagne, J-M. Galano, C. Oger, J. Thireau, S. Matecky, H. Dridi, J. Roy, V. Bultel-Ponce, A. Guy, T. Durand, J-Y. Le Guennec
European Patent 05 April 2022- EP22305460.2 ;

Publications 2017

Amor, A. M. C.-D., Aguayo, E., Collado-González, J., Guy, A., Galano, J.-M., Durand, T. & Gil-Izquierdo, Á. Impact of processing conditions on the phytoprostanes profile of three types of nut kernels. Free Radic. Res. 51, 141–147 (2017).

Bosviel, R., Joumard-Cubizolles, L., Chinetti-Gbaguidi, G., Bayle, D., Copin, C., Hennuyer, N., Duplan, I., Staels, B., Zanoni, G., Porta, A., Balas, L., Galano, J. M., Oger, C., Mazur, A., Durand, T. & Gladine, C. DHA-derived oxylipins, neuroprostanes and protectins, differentially and dose-dependently modulate the inflammatory response in human macrophages : Putative mechanisms through PPAR activation. Free Radic Biol Med 103, 146–154 (2017).

Collado-González, J., Grosso, C., Valentão, P., Andrade, P. B., Ferreres, F., Durand, T., Guy, A., Galano, J.-M., Torrecillas, A. & Gil-Izquierdo, Á. Inhibition of α-glucosidase and α-amylase by Spanish extra virgin olive oils : The involvement of bioactive compounds other than oleuropein and hydroxytyrosol. Food Chem. 235, 298–307 (2017).

Cuyamendous, C., Leung, K. S., Bultel-Poncé, V., Guy, A., Durand, T., Galano, J.-M., Lee, J. C.-Y. & Oger, C. Total Synthesis and in Vivo Quantitation of Phytofurans Derived from α-Linolenic Acid. Eur. J. Org. Chem. 2017, 2486–2490 (2017).

De Las Heras-Gomez, I., Medina, S., Casas-Pina, T., Marin-Soler, L., Tomas, A., Martinez-Hernandez, P., Oger, C., Galano, J. M., Durand, T., Jimeno, L., Llorente, S., Lozoya, E., Ferreres, F. & Gil-Izquierdo, A. Potential applications of lipid peroxidation products - F4-neuroprostanes, F3-neuroprostanesn-6 DPA, F2-dihomo-isoprostanes and F2-isoprostanes - in the evaluation of the allograft function in renal transplantation. Free Radic Biol Med 104, 178–184 (2017).

Demion, M., Oger, C., Vigor, C., Thireau, J., Guennec, J.-Y. L., Durand, T., Galano, J.-M. & Lee, J. C.-Y. Two sides of the same coin : NEO-PUFAs in Rett syndrome and post-infarction cardiac arrhythmias. Eur. J. Lipid Sci. Technol. 119, n/a-n/a (2017).

Galano, J.-M., Lee, Y. Y., Oger, C., Vigor, C., Vercauteren, J., Durand, T., Giera, M. & Lee, J. C.-Y. Isoprostanes, neuroprostanes and phytoprostanes : An overview of 25years of research in chemistry and biology. Prog. Lipid Res. 68, 83–108 (2017).

Galano, J.-M., Oger, C., Bultel-Poncé, V., REVERSAT, G., Guy, A., Vercauteren, J., Vigor, C. & Durand, T. F3-Isoprostanes and 4-Neuroprostanes : Non-enzymatic Cyclic Oxygenated metabolites of Omega-3 polyunsaturated Fatty Acids  : biomarkers and Bioactive Lipids. Fats Life 22, 25–32 (2017).

Garcia-Flores, L. A., Medina, S., Martinez-Hernandez, P., Oger, C., Galano, J. M., Durand, T., Casas-Pina, T., Ferreres, F. & Gil-Izquierdo, A. Snapshot situation of oxidative degradation of the nervous system, kidney, and adrenal glands biomarkers-neuroprostane and dihomo-isoprostanes-urinary biomarkers from infancy to elderly adults. Redox Biol 11, 586–591 (2017).

Joumard-Cubizolles, L., Lee, J. C.-Y., Vigor, C., Leung, H. H., Bertrand-Michel, J., Galano, J.-M., Mazur, A., Durand, T. & Gladine, C. Insight into the contribution of isoprostanoids to the health effects of omega 3 PUFAs. Prostaglandins Other Lipid Mediat. 133, 111–122 (2017).

Lai, K. P., Lee, J. C.-Y., Wan, H. T., Li, J. W., Wong, A. Y.-M., Chan, T. F., Oger, C., Galano, J.-M., Durand, T., Leung, K. S., Leung, C. C., Li, R. & Wong, C. K.-C. Effects of in Utero PFOS Exposure on Transcriptome, Lipidome, and Function of Mouse Testis. Environ. Sci. Technol. 51, 8782–8794 (2017).

Leung, K. S., Chan, H. F., Leung, H. H., Galano, J.-M., Oger, C., Durand, T. & Lee, J. C.-Y. Short-time UVA exposure to human keratinocytes instigated polyunsaturated fatty acid without inducing lipid peroxidation. Free Radic. Res. 51, 269–280 (2017).

Marhuenda, J., Medina, S., Martínez-Hernández, P., Arina, S., Zafrilla, P., Mulero, J., Oger, C., Galano, J.-M., Durand, T., Ferreres, F. & Gil-Izquierdo, A. Melatonin and hydroxytyrosol protect against oxidative stress related to the central nervous system after the ingestion of three types of wine by healthy volunteers. Food Funct. 8, 64–74 (2017).

Marhuenda, J., Medina, S., Martínez-Hernández, P., Arina, S., Zafrilla, P., Mulero, J., Oger, C., Galano, J.-M., Durand, T., Solana, A., Ferreres, F., López-García, J. J. & Gil-Izquierdo, A. Effect of the dietary intake of melatonin- and hydroxytyrosol-rich wines by healthy female volunteers on the systemic lipidomic-related oxylipins. Food Funct 8, 3745–3757 (2017).

Medina, S., Collado-González, J., Ferreres, F., Londoño-Londoño, J., Jiménez-Cartagena, C., Guy, A., Durand, T., Galano, J.-M. & Gil-Izquierdo, A. Quantification of phytoprostanes – bioactive oxylipins – and phenolic compounds of Passiflora edulis Sims shell using UHPLC-QqQ-MS/MS and LC-IT-DAD-MS/MS. Food Chem. 229, 1–8 (2017).

Pérez-Berezo, T., Pujo, J., Martin, P., Le Faouder, P., Galano, J.-M., Guy, A., Knauf, C., Tabet, J. C., Tronnet, S., Barreau, F., Heuillet, M., Dietrich, G., Bertrand-Michel, J., Durand, T., Oswald, E. & Cenac, N. Identification of an analgesic lipopeptide produced by the probiotic Escherichia coli strain Nissle 1917. Nat. Commun. 8, (2017).

Pinciroli, M., Domínguez-Perles, R., Abellán, A., Guy, A., Durand, T., Oger, C., Galano, J. M., Ferreres, F. & Gil-Izquierdo, A. Comparative Study of the Phytoprostane and Phytofuran Content of indica and japonica Rice ( Oryza sativa L.) Flours. J. Agric. Food Chem. 65, 8938–8947 (2017).

Rosell, M., Villa, M., Durand, T., Galano, J.-M., Vercauteren, J. & Crauste, C. Total Syntheses of Two bis-Allylic-Deuterated DHA Analogues. Asian J. Org. Chem. 6, 322–334 (2017).

Roy, J., Fauconnier, J., Oger, C., Farah, C., Angebault-Prouteau, C., Thireau, J., Bideaux, P., Scheuermann, V., Bultel-Poncé, V., Demion, M., Galano, J.-M., Durand, T., Lee, J. C.-Y. & Le Guennec, J.-Y. Non-enzymatic oxidized metabolite of DHA, 4(RS)-4-F4t-neuroprostane protects the heart against reperfusion injury. Free Radic. Biol. Med. 102, 229–239 (2017).

Sánchez-Illana, Á., Thayyil, S., Montaldo, P., Jenkins, D., Quintás, G., Oger, C., Galano, J.-M., Vigor, C., Durand, T., Vento, M. & Kuligowski, J. Novel free-radical mediated lipid peroxidation biomarkers in newborn plasma. Anal. Chim. Acta 996, 88–97 (2017).

Shamseddin, A., Crauste, C., Durand, E., Villeneuve, P., Dubois, G., Durand, T., Vercauteren, J. & Veas, F. Resveratrol formulated with a natural deep eutectic solvent inhibits active matrix metalloprotease-9 in hormetic conditions : Resveratrol NADES formulation and hormesis. Eur. J. Lipid Sci. Technol. 119, 1700171 (2017).

Publications 2011 /2016

• 2016

« Dihydroxylated E,E,Z-docosatrienes. An overview of their synthesis and biological significance », BALAS L., DURAND T. Prog Lipid Res. 61, 1-18 (2016).

« Non enzymatic metabolites of polyunsaturated fatty acids : friend or foe », BULTEL-PONCE V., DURAND T., GUY A., OGER C., GALANO J. M. Ocl-Oilseeds and Fats Crops and Lipids. 23(2016).

« Effect of the season on the free phytoprostane content in Cornicabra extra virgin olive oil from deficit-irrigated olive trees », COLLADO-GONZALEZ J., PEREZ-LOPEZ D., MEMMI H., GIJON M. C., MEDINA S., DURAND T., GUY A., GALANO J. M., FERNANDEZ D. J., CARRO F., FERRERES F., TORRECILLAS A., GIL-IZQUIERDO A. J. Sci. Food Agr. 96, 1585-1592 (2016).

« Abnormal N-glycosylation pattern for brain nucleotide pyrophosphatase-5 (NPP-5) in Mecp2-mutant murine models of Rett syndrome », CORTELAZZO A., DE FELICE C., GUERRANTI R., SIGNORINI C., LEONCINI S., PECORELLI A., SCALABRI F., MADONNA M., FILOSA S., DELLA GIOVAMPAOLA C., CAPONE A., DURAND T., MIRASOLE C., ZOLLA L., VALACCHI G., CICCOLI L., GUY J., D’ESPOSITO M., HAYEK J. Neurosci Res. 105, 28-34 (2016).

« Omega-3 polyunsaturated lipophenols, how and why ? », CRAUSTE C., ROSELL M., DURAND T., VERCAUTEREN J. Biochimie. 120, 62-74 (2016).

« Rett syndrome : An autoimmune disease ? », DE FELICE C., LEONCINI S., SIGNORINI C., CORTELAZZO A., ROVERO P., DURAND T., CICCOLI L., PAPINI A. M., HAYEK J. Autoimmun Rev. 15, 411-416 (2016).

« Simultaneous quantitative profiling of 20 isoprostanoids from omega-3 and omega-6 polyunsaturated fatty acids by LC-MS/MS in various biological samples », DUPUY A., LE FAOUDER P., VIGOR C., OGER C., GALANO J. M., DRAY C., LEE J. C., VALET P., GLADINE C., DURAND T., BERTRAND-MICHEL J. Anal Chim Acta. 921, 46-58 (2016).

« Assessment of oxidative stress biomarkers - neuroprostanes and dihomo-isoprostanes - in the urine of elite triathletes after two weeks of moderate-altitude training », GARCIA-FLORES L. A., MEDINA S., CEJUELA R., MARTINEZ-SANZ J. M., OGER C., GALANO J. M., DURAND T., CASAS-PINA T., MARTINEZ-HERNANDEZ P., FERRERES F., GIL-IZQUIERDO A. Free Radic Res. 50, 485-494 (2016).

« Non-enzymatic cyclic oxygenated metabolites of omega-3 polyunsaturated fatty acid : Bioactive drugs ? », ROY J., LE GUENNEC J. Y., GALANO J. M., THIREAU J., BULTEL-PONCE V., DEMION M., OGER C., LEE J. C., DURAND T. Biochimie. 120, 56-61 (2016).

« MECP2 Duplication Syndrome : Evidence of Enhanced Oxidative Stress. A Comparison with Rett Syndrome », SIGNORINI C., DE FELICE C., LEONCINI S., MOLLER R. S., ZOLLO G., BUONI S., CORTELAZZO A., GUERRANTI R., DURAND T., CICCOLI L., D’ESPOSITO M., RAVN K., HAYEK J. PLoS One. 11, e0150101 (2016).

• 2015

« Nonenzymatic alpha-Linolenic Acid Derivatives from the Sea : Macroalgae as Novel Sources of Phytoprostanes », BARBOSA M., COLLADO-GONZALEZ J., ANDRADE P. B., FERRERES F., VALENTAO P., GALANO J. M., DURAND T., GIL-IZQUIERDO A. J Agric Food Chem. 63, 6466-6474 (2015).

« Phytoprostanes in almonds : identification, quantification, and impact of cultivar and type of cultivation », CARRASCO-DEL AMOR A. M., COLLADO-GONZALEZ J., AGUAYO E., GUY A., GALANO J. M., DURAND T., GIL-IZQUIERDO A. Rsc Advances. 5, 51233-51241 (2015).

« Hyperoxia Elevates Adrenic Acid Peroxidation in Marine Fish and Is Associated with Reproductive Pheromone Mediators », CHUNG M. L. S., GALANO J. M., OGER C., DURAND T., LEE J. C. Y. Marine Drugs. 13, 2215-2232 (2015).

« Phytoprostanes », COLLADO-GONZALEZ J., DURAND T., FERRERES F., MEDINA S., TORRECILLAS A., GIL-IZQUIERDO A. Lipid Technology. 27, 127-130 (2015).

« New UHPLC-QqQ-MS/MS method for quantitative and qualitative determination of free phytoprostanes in foodstuffs of commercial olive and sunflower oils », COLLADO-GONZALEZ J., MEDINA S., DURAND T., GUY A., GALANO J. M., TORRECILLAS A., FERRERES F., GIL-IZQUIERDO A. Food Chemistry. 178, 212-220 (2015).

« The phytoprostane content in green table olives is influenced by Spanish-style processing and regulated deficit irrigation », COLLADO-GONZALEZ J., MORIANA A., GIRON I. F., CORELL M., MEDINA S., DURAND T., GUY A., GALANO J. M., VALERO E., GARRIGUES T., FERRERES F., MORENO F., TORRECILLAS A., GIL-IZQUIERDO A. Lwt-Food Science and Technology. 64, 997-1003 (2015).

« Water Deficit during Pit Hardening Enhances Phytoprostanes Content, a Plant Biomarker of Oxidative Stress, in Extra Virgin Olive Oil », COLLADO-GONZALEZ J., PEREZ-LOPEZ D., MEMMI H., GIJON M. C., MEDINA S., DURAND T., GUY A., GALANO J. M., FERRERES F., TORRECILLAS A., GIL-IZQUIERDO A. J. Agr. Food Chem. 63, 3784-3792 (2015).

« Synthesis and discovery of phytofurans : metabolites of alpha-linolenic acid peroxidation », CUYAMENDOUS C., LEUNG K. S., DURAND T., LEE J. C. Y., OGER C., GALANO J. M. Chemical Communications. 51, 15696-15699 (2015).

« Oxidative stress : a hallmark of Rett syndrome », DE FELICE C., SIGNORINI C., LEONCINI S., DURAND T., CICCOLI L., HAYEK J. Future Neurol. 10, 179-182 (2015).

« Total Syntheses and In Vivo Quantitation of Novel Neurofuran and Dihomo-isofuran Derived from Docosahexaenoic Acid and Adrenic Acid », DE LA TORRE A., LEE Y. Y., MAZZONI A., GUY A., BULTEL-PONCÉ V., DURAND T., OGER C., LEE J. C.-Y., GALANO J.-M. Chemistry A European Journal. 21, 2442-2446 (2015).

« Regioselective synthesis of diacylglycerol rosmarinates and evaluation of their antioxidant activity in fibroblasts », DURAND E., BAYRASY C., LAGUERRE M., BAROUH N., LECOMTE J., DURAND T., BALAS L., WRUTNIAK-CABELLO C., CABELLO G., VILLENEUVE P. European Journal of Lipid Science and Technology. 117, 1159-1170 (2015).

« Non-enzymatic cyclic oxygenated metabolites of adrenic, docosahexaenoic, eicosapentaenoic and alpha-linolenic acids ; bioactivities and potential use as biomarkers », GALANO J. M., LEE J. C. Y., GLADINE C., COMTE B., LE GUENNEC J. Y., OGER C., DURAND T. Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids. 1851, 446-455 (2015).

« Special Issue on »Analytical Methods for Oxidized Biomolecules and Antioxidants« The use of isoprostanoids as biomarkers of oxidative damage, and their role in human dietary intervention studies », GALANO J. M., LEE Y. Y., DURAND T., LEE J. C. Y. Free Radical Research. 49, 583-598 (2015).

« Facile synthesis of cyclopentenone B1- and L1-type phytoprostanes », GUY A., FLANAGAN S., DURAND T., OGER C., GALANO J.-M. Front Chem. 3, 1-10 (2015).

« Differential Mobility Separation of Leukotrienes and Protectins », JONASDOTTIR H. S., PAPAN C., FABRITZ S., BALAS L., DURAND T., HARDARDOTTIR I., FREYSDOTTIR J., GIERA M. Analytical Chemistry. 87, 5036-5040 (2015).

« Prenatal exposure to the contaminant perfluorooctane sulfonate elevates lipid peroxidation during mouse fetal development but not in the pregnant dam », LEE Y. Y., WONG C. K., OGER C., DURAND T., GALANO J. M., LEE J. C. Free Radic Res. 49, 1015-1025 (2015).

« Cytokine Dysregulation in MECP2- and CDKL5-Related Rett Syndrome : Relationships with Aberrant Redox Homeostasis, Inflammation, and omega-3 PUFAs », LEONCINI S., DE FELICE C., SIGNORINI C., ZOLLO G., CORTELAZZO A., DURAND T., GALANO J. M., GUERRANTI R., ROSSI M., CICCOLI L., HAYEK J. Oxid Med Cell Longev. 2015, 421624 (2015).

« Current development in non-enzymatic lipid peroxidation products, isoprostanoids and isofuranoids, in novel biological samples », LEUNG K. S., GALANO J. M., DURAND T., LEE J. C. Free Radic Res. 49, 816-826 (2015).

« Dependency of Phytoprostane Fingerprints of Must and Wine on Viticulture and Enological Processes », MARHUENDA J., MEDINA S., DIAZ-CASTRO A., MARTINEZ-HERNANDEZ P., ARINA S., ZAFRILLA P., MULERO J., OGER C., GALANO J. M., DURAND T., FERRERES F., GIL-IZQUIERDO A. J. Agr. Food Chem. 63, 9022-9028 (2015).

« Dihomo-isoprostanes-nonenzymatic metabolites of AdA-are higher in epileptic patients compared to healthy individuals by a new ultrahigh pressure liquid chromatography-triple quadrupole-tandem mass spectrometry method », MEDINA S., DE MIGUEL-ELIZAGA I., OGER C., GALANO J.-M., DURAND T., MARTINEZ-VILLANUEVA M., CASTILLO M. L. G.-D., VILLEGAS-MARTINEZ I., FERRERES F., MARTINEZ-HERNANDEZ P., GIL-IZQUIERDO A. Free Rad Biol Med. 79, 154-163 (2015).

« Profiling and relative quantification of multiply nitrated and oxidized fatty acids », MILIC I., GRIESSER E., VEMULA V., IEDA N., NAKAGAWA H., MIYATA N., GALANO J. M., OGER C., DURAND T., FEDOROVA M. Anal Bioanal Chem. 407, 5587-5602 (2015).

« Nonenzymatic lipid mediators, neuroprostanes, exert the antiarrhythmic properties of docosahexaenoic acid », ROY J., OGER C., THIREAU J., ROUSSEL J., MERCIER-TOUZET O., FAURE D., PINOT E., FARAH C., TABER D. F., CRISTOL J. P., LEE J. C., LACAMPAGNE A., GALANO J. M., DURAND T., LE GUENNEC J. Y. Free Radic Biol Med. 86, 269-278 (2015).

« Polymeric nanocapsules prevent oxidation of core-loaded molecules : evidence based on the effects of docosahexaenoic acid and neuroprostane on breast cancer cells proliferation », ROY J., OLIVEIRA L. T., OGER C., GALANO J. M., BULTEL-PONCE V., RICHARD S., GUIMARAES A. G., VILELA J. M., ANDRADE M. S., DURAND T., BESSON P., MOSQUEIRA V. C., LE GUENNEC J. Y. J Exp Clin Cancer Res. 34, 155 (2015).

« Erythrocyte cytoskeletal-plasma membrane protein network in Rett syndrome : effects of -3 polyunsaturated fatty acids », A. CORTELAZZO, C. DE FELICE, R. GUERRANTI, R. LEONCINI, A. BARDUCCI, A. GAGLIARDI, A. ARMINI, S. LEONCINI, C. SIGNORINI, G. ZOLLO, A. PECORELLI, E. PACCAGNINI, M. GENTILE, L. BINI T. DURAND, J-M. GALANO, M. ROSSI, G. VALACHI, L. CICCOLI, J. HAYEK. Current Proteomics, 12, 217-226 (2015).

• 2014

« Oxidative Stress and Rett Syndrome », DE FELICE C., SIGNORINI C., LEONCINI S., PECORELLI A., DURAND T., VALACCHI G., CICCOLI L., HAYEK J. Minerva Pediatr. 66, 41-62 (2014).

« Confusion between protectin D1 (PD1) and its isomer protectin DX (PDX). An overview on the dihydroxy-docosatrienes described to date », BALAS L., GUICHARDANT M., DURAND T., LAGARDE M. Biochimie. 99C, 1-7 (2014).

« Acidi grassi polinsaturi w-3 e stato infiammatorio subclinico nella sindrome di Rett », CORTELAZZO A., DE FELICE C., SIGNORINI C., GUERRANTI R., LEONCINI S., PECORELLI A., DURAND T., GALANO J.-M., OGER C., ZOLLO G., MONTOMOLI B., LANDI C., BINI L., VALACCHI G., CICCOLI L., HAYEK J. L’INTEGRATORE NUTRIZIONALE. 26-34 (2014).

« Synthesis and Evaluation of Polyunsaturated Fatty Acid-Phenol Conjugates as Anti-Carbonyl-Stress Lipophenols », CRAUSTE C., VIGOR C., BRABET P., PICQ M., LAGARDE M., HAMEL C., DURAND T., VERCAUTEREN J. European Journal of Organic Chemistry. 4548-4561 (2014).

« A Versatile and Stereocontrolled Total Synthesis of Dihydroxylated Docosatrienes Containing a Conjugated E,E,Z-Triene », DAYAKER G., DURAND T., BALAS L. Chemistry-a European Journal. 20, 2879-2887 (2014).

« Total Synthesis of Neuroprotectin D1 Analogues Derived from Omega-6 Docosapentaenoic Acid (DPA) and Adrenic Acid (AdA) from a Common Pivotal, Late-Stage Intermediate », DAYAKER G., DURAND T., BALAS L. J Org Chem. 79, 2657-2665 (2014).

« Oxidative brain damage in Mecp2-mutant murine models of Rett syndrome », DE FELICE C., DELLA RAGIONE F., SIGNORINI C., LEONCINI S., PECORELLI A., CICCOLI L., SCALABRI F., MARRACINO F., MADONNA M., BELMONTE G., RICCERI L., DE FILIPPIS B., LAVIOLA G., VALACCHI G., DURAND T., GALANO J. M., OGER C., GUY A., BULTEL-PONCE V., GUY J., FILOSA S., HAYEK J., D’ESPOSITO M. Neurobiol Dis. 68C, 66-77 (2014).

« [Oxidative stress and Rett syndrome.] », DE FELICE C., SIGNORINI C., LEONCINI S., PECORELLI A., DURAND T., VALACCHI G., CICCOLI L., HAYEK J. Minerva Pediatr. 66, 41-62 (2014).

« Synthesis, Discovery, and Quantitation of Dihomo-Isofurans : Biomarkers for In Vivo Adrenic Acid Peroxidation », DE LA TORRE A., LEE Y. Y., OGER C., SANGILD P. T., DURAND T., LEE J. C. Y., GALANO J. M. Angewandte Chemie-International Edition. 53, 6249-6252 (2014).

« Development of the First Oral Bioprecursors of Bis-alkylguanidine Antimalarial Drugs », DEGARDIN M., WEIN S., DUCKERT J. F., MAYNADIER M., GUY A., DURAND T., ESCALE R., VIAL H., VO-HOANG Y. ChemMedChem. 9, 300-304 (2014).

« Lipid Profiling following Intake of the Omega 3 Fatty Acid DHA Identifies the Peroxidized Metabolites F4-Neuroprostanes as the Best Predictors of Atherosclerosis Prevention », GLADINE C., NEWMAN J. W., DURAND T., PEDERSEN T. L., GALANO J. M., DEMOUGEOT C., BERDEAUX O., PUJOS-GUILLOT E., MAZUR A., COMTE B. PLoS One. 9, e89393 (2014).

« Oxygenated Metabolites of n-3 Polyunsaturated Fatty Acids as Potential Oxidative Stress Biomarkers : Total Synthesis of 8-F3t -IsoP, 10-F4t -NeuroP and [D4 ]-10-F4t -NeuroP », GUY A., OGER C., HEPPEKAUSEN J., SIGNORINI C., DE FELICE C., FURSTNER A., DURAND T., GALANO J. M. Chemistry. 20, 6374-6380 (2014).

« Recent Approaches To The Total Synthesis Of Phytoprostanes, Isoprostanes And Neuroprostanes As Important Products Of Lipid Oxidative Stress And Biomarkers Of Disease », JAHN E., DURAND T., GALANO J.-M., JAHN U. Chem. Listy. 108, 301-319 (2014).

« Role of the Non-enzymatic Metabolite of Eicosapentaenoic Acid, 5-epi-5-F3t-Isoprostane in the Regulation of [3H]d-Aspartate Release in Isolated Bovine Retina », JAMIL J., BANKHELE P., SALVI A., MANNIX J. E., OGER C., GUY A., GALANO J.-M., DURAND T., NJIE-MBYE Y., OHIA S., OPERE C. Neurochem Res. 39, 2360-2369 (2014).

« Effects of omega -3 PUFAs Supplementation on Myocardial Function and Oxidative Stress Markers in Typical Rett Syndrome », MAFFEI S., DE FELICE C., CANNARILE P., LEONCINI S., SIGNORINI C., PECORELLI A., MONTOMOLI B., LUNGHETTI S., CICCOLI L., DURAND T., FAVILLI R., HAYEK J. Mediators Inflamm. 2014, 983178 (2014).

« Nonenzymatic oxygenated metabolites of alpha-linolenic acid B1- and L1-phytoprostanes protect immature neurons from oxidant injury and promote differentiation of oligodendrocyte progenitors through PPAR-gamma activation », MINGHETTI L., SALVI R., LAVINIA SALVATORI M., AJMONE-CAT M. A., DE NUCCIO C., VISENTIN S., BULTEL-PONCE V., OGER C., GUY A., GALANO J. M., GRECO A., BERNARDO A., DURAND T. Free Radic Biol Med. 73, 41-50 (2014).

« A Huge PVDF Adsorption Difference Between Resveratrol and epsilon-Viniferin Allows to Quantitatively Purify Them and to Assess Their Anti-Tyrosinase Property », MOREL-SALMI C., JULIA A., VIGOR C., VERCAUTEREN J. Chromatographia. 77, 957-961 (2014).

« Altered erythrocyte membrane fatty acid profile in typical Rett syndrome : Effects of omega-3 polyunsaturated fatty acid supplementation », SIGNORINI C., DE FELICE C., LEONCINI S., DURAND T., GALANO J.-M., CORTELAZZO A., ZOLLO G., GUERRANTI R., GONNELLI S., CAFFARELLI C., ROSSI M., PECORELLI A., VALACCHI G., CICCOLI L., HAYEK J. Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA). 91, 183-193 (2014).

« Redox imbalance and morphological changes in skin fibroblasts in typical Rett syndrome », SIGNORINI C., LEONCINI S., DE FELICE C., PECORELLI A., MELONI I., ARIANI F., MARI F., AMABILE S., PACCAGNINI E., GENTILE M., BELMONTE G., ZOLLO G., VALACCHI G., DURAND T., GALANO J. M., CICCOLI L., RENIERI A., HAYEK J. Oxid Med Cell Longev. 2014, 195935 (2014).

« Flavonoïds from Euphorbia guyoniana Boissier & Reuter », SMARA O., JULIA A., MORAL-SALMI C., VIGOR C., VERCAUTEREN J., BELGACEM L. J Life Sci. 8, 544-551 (2014).

« Non-enzymatic lipid oxidation products in biological systems : assessment of the metabolites from polyunsaturated fatty acids », VIGOR C., BERTRAND-MICHEL J., PINOT E., OGER C., VERCAUTEREN J., LE FAOUDER P., GALANO J. M., LEE J. C., DURAND T. J Chromatogr B Analyt Technol Biomed Life Sci. 964, 65-78 (2014).

• 2013

« Erythrocyte Shape Abnormalities, Membrane Oxidative Damage, and beta -Actin Alterations : An Unrecognized Triad in Classical Autism », CICCOLI L., DE FELICE C., PACCAGNINI E., LEONCINI S., PECORELLI A., SIGNORINI C., BELMONTE G., GUERRANTI R., CORTELAZZO A., GENTILE M., ZOLLO G., DURAND T., VALACCHI G., ROSSI M., HAYEK J. Mediators Inflamm. 2013, 432616 (2013).

« Effects of omega -3 Polyunsaturated Fatty Acids on Plasma Proteome in Rett Syndrome », DE FELICE C., CORTELAZZO A., SIGNORINI C., GUERRANTI R., LEONCINI S., PECORELLI A., DURAND T., GALANO J. M., OGER C., ZOLLO G., MONTOMOLI B., LANDI C., BINI L., VALACCHI G., CICCOLI L., HAYEK J. Mediators Inflamm. 2013, 723269 (2013).

« Acidi grassi ù-3 nella sindrome di Rett. Studio clinico al primo stadio della malattia », DE FELICE C., LEONCINI S., SIGNORINI C., PECORELLI A., DURAND T., GALANO J.-M., OGER C., CORTELAZZO A., MONTOMOLI B., ZOLLO G., VALACCHI G., CICCOLI L., HAYEK J. L’INTEGRATORE NUTRIZIONALE. 16, 9-14 (2013).

« Fatty Acids and Autism Spectrum Disorders : The Rett Syndrome Conundrum », DE FELICE C., SIGNORINI C., LEONCINI S., PECORELLI A., DURAND T., GALANO J.-M., BULTEL-PONCÉ V., GUY A., OGER C., ZOLLO G., VALACCHI G., CICCOLI L., HAYEK J. food and nutrition sciences. 71-75 (2013).

« F-2-Dihomo-isoprostanes and brain white matter damage in stage 1 Rett syndrome », DURAND T., DE FELICE C., SIGNORINI C., OGER C., BULTEL-PONCE V., GUY A., GALANO J. M., LEONCINI S., CICCOLI L., PECORELLI A., VALACCHI G., HAYEK J. Biochimie. 95, 86-90 (2013).

« Isoprostanes and neuroprostanes : total synthesis, biological activity and biomarkers of oxidative stress in humans », GALANO J. M., MAS E., BARDEN A., MORI T. A., SIGNORINI C., DE FELICE C., BARRETT A., OPERE C., PINOT E., SCHWEDHELM E., BENNDORF R., ROY J., LE GUENNEC J. Y., OGER C., DURAND T. Prostaglandins Other Lipid Mediat. 107, 95-102 (2013).

« Are Alkyne Reductions Chemo-, Regio-, and Stereoselective Enough To Provide Pure (Z)-Olefins in Polyfunctionalized Bioactive Molecules ? », OGER C., BALAS L., DURAND T., GALANO J.-M. Chem. Rev. 113, 1313-1350 (2013).

« Regulation of Potassium-induced [3H]D-Aspartate Release from Isolated Bovine Retina by 5-epi-5-F3t-Isoprostane : Role of Prostanoid Receptors », OPERE C. A., JAMIL J., SALVI A., BANKHELE P., FLOWERS A., FLOYD N., DURAND T., GALANO J.-M., GUY A., OGER C., NJIE-MBYE Y. F., KULKARNI M. S., OHIA S. FASEB J. 27, 1174.1176 (2013).

« Isoprostanes and 4-Hydroxy-2-nonenal : Markers or Mediators of Disease ? Focus on Rett Syndrome as a Model of Autism Spectrum Disorder », SIGNORINI C., DE FELICE C., DURAND T., OGER C., GALANO J.-M., LEONCINI S., PECORELLI A., VALACCHI G., CICCOLI L., HAYEK J. Oxid. Med. Cell. Longev. 2013, 1-10 (2013).

• 2012

« Is there a role for isofurans and neuroprostanes in pre-eclampsia and normal pregnancy ? », BARDEN A. E., CORCORAN T. B., MAS E., DURAND T., GALANO J. M., ROBERTS L. J., PAECH M., MUCHATUTA N. A., PHILLIPS M., MORI T. A. Antioxid Redox Signal. 16, 165-169 (2012).

« The Fraction of alpha-Linolenic Acid Present in the sn-2 Position of Structured Triacylglycerols Decreases in Lymph Chylomicrons and Plasma Triacylglycerols during the Course of Lipid Absorption in Rats », COUEDELO L., VAYSSE C., VAIQUE E., GUY A., GOSSE I., DURAND T., PINET S., CANSELL M., COMBE N. J Nutr. 142, 70-75 (2012).

« Partial rescue of Rett syndrome by omega-3 polyunsaturated fatty acids (PUFAs) oil », DE FELICE C., SIGNORINI C., DURAND T., CICCOLI L., LEONCINI S., D’ESPOSITO M., FILOSA S., OGER C., GUY A., BULTEL-PONCE V., GALANO J. M., PECORELLI A., DE FELICE L., VALACCHI G., HAYEK J. Genes Nutr. 7, 447-458 (2012).

« The Role of Oxidative Stress in Rett Syndrome : an overview », DE FELICE C., SIGNORINI C., LEONCINI S., PECORELLI A., DURAND T., VALACCHI G., CICCOLI L., HAYEK J. Ann. NY Acad. Sci. 1259, 121-135 (2012).

« Evaluation of bis-alkylamidoxime o-alkylsulfonates as orally available antimalarials », DEGARDIN M., WEIN S., GOUNI S., TRAN VAN BA C., DUCKERT J. F., DURAND T., ESCALE R., VIAL H., VO-HOANG Y. ChemMedChem. 7, 991-1001 (2012).

« Regulation of K+-induced 3H D-Aspartate Release by Synthetic Neuroprostanes in Isolated Bovine Retina », FLOWERS A. F., FLOYD N., KEDEY E., JAMIL J., DURAND T., GALANO J.-M., GUY A., NJIE-MBYE Y., OHIA S. E., OPERE C. A. Faseb J. 26, 843.844 (2012).

« Regulation of 3H d-aspartate release by the 5-F(2t)-isoprostane and its 5-epimer in isolated bovine retina », JAMIL J., WRIGHT A., HARRISON N., KEGEY E., FLOWERS A. F., FLYOD N. J., KOTERA C., GUY A., GALANO J. M., DURAND T., NJIE-MBYE Y. F., OHIA S. E., OPERE C. A. Neurochem Res. 37, 574-582 (2012).

« Systemic lipid peroxidation in mild cognitive impairment (MCI) and Alzheimer’s disease (AD) », LEONCINI S., DE FELICE C., SIGNORINI C., PECORELLI A., DURAND T., GALANO J. M., OGER C., BULTEL-PONCE V., GUY A., BOSCHI S., CICCOLI L., HAYEK J. Eur. J. Neurol. 19, 101-101 (2012).

« Quercetin accumulates in nuclear structures and triggers specific gene expression in epithelial cells », NOTAS G., NIFLI A. P., KAMPA M., PELEKANOU V., ALEXAKI V. I., THEODOROPOULOS P., VERCAUTEREN J., CASTANAS E. J Nutr Biochem. 23, 656-666 (2012).

« Total Syntheses of Isoprostanes Derived from Adrenic Acid and EPA », OGER C., BULTEL-PONCÉ V., GUY A., DURAND T., GALANO J.-M. Eur. J. Org. Chem. 2012, 2621-2634 (2012).

« Tuberculosis : The drug development pipeline at a glance. », VILLEMAGNE B., CRAUSTE C., FLIPO M., BAULARD A., DÉPREZ B., WILLAND N. Eur. J. Med. Chem. 51, 1-16 (2012).

• 2011

« The effects of oxidation products of arachidonic acid and n3 fatty acids on vascular and platelet function », BARDEN A., MAS E., HENRY P., DURAND T., GALANO J. M., ROBERTS L. J., CROFT K. D., MORI T. A. Free Radic Res. 45, 469-476 (2011).

« Synthesis of cysteinyl leukotrienes in human endothelial cells : subcellular localization and autocrine signaling through the CysLT2 receptor », CARNINI C., ACCOMAZZO M. R., BORRONI E., VITELLARO-ZUCCARELLO L., DURAND T., FOLCO G., ROVATI G. E., CAPRA V., SALA A. Faseb J. 25, 3519-3528 (2011).

« Are Isofurans and Neuroprostanes Increased After Subarachnoid Hemorrhage and Traumatic Brain Injury ? », CORCORAN T. B., MAS E., BARDEN A. E., DURAND T., GALANO J. M., ROBERTS L. J., PHILLIPS M., HO K. M., MORI T. A. Antioxid Redox Signal. 15, 2663-2667 (2011).

« Asymmetric synthesis of new B-lactam lipopeptides as bacterial signal peptidase I inhibitors. », CRAUSTE C., FROEYEN M., ANNÉ J., HERDEWIJN P. Eur. J. Org. Chem. 19, 3437-3449 (2011).

« Synthesis of 2’,3’-Dideoxynucleoside Phosphoesters Using H-Phosphonate Chemistry on Soluble Polymer Support. », CRAUSTE C., PÉRIGAUD C., PEYROTTES S. J. Org. Chem. 76, 997-1000 (2011).

« F2-dihomo-isoprostanes as potential early biomarkers of lipid oxidative damage in Rett syndrome », DE FELICE C., SIGNORINI C., DURAND T., OGER C., GUY A., BULTEL-PONCE V., GALANO J. M., CICCOLI L., LEONCINI S., D’ESPOSITO M., FILOSA S., PECORELLI A., VALACCHI G., HAYEK J. J Lipid Res. 52, 2287-2297 (2011).

« Isoprostanes and phytoprostanes : Bioactive lipids », DURAND T., BULTEL-PONCE V., GUY A., EL FANGOUR S., ROSSI J. C., GALANO J. M. Biochimie. 93, 52-60 (2011).

« The Alphabet of Galactolipids in Arabidopsis Thaliana », IBRAHIM A., SCHÜTZ A.-L., GALANO J.-M., HERRFURTH C., FEUSSNER K., DURAND T., BRODHUN F., FEUSSNER I. Frontiers in plant science. 2, 1-24 (2011).

« Symmetrical choline-derived dications display strong anti-kinetoplastid activity », IBRAHIM H. M., AL-SALABI M. I., EL SABBAGH N., QUASHIE N. B., ALKHALDI A. A., ESCALE R., SMITH T. K., VIAL H. J., DE KONING H. P. J Antimicrob Chemother. 66, 111-125 (2011).

« Novel oligomeric proanthocyanidin derivatives interact with membrane androgen sites and induce regression of hormone-independent prostate cancer », KAMPA M., THEODOROPOULOU K., MAVROMATI F., PELEKANOU V., NOTAS G., LAGOUDAKI E. D., NIFLI A. P., MOREL-SALMI C., STATHOPOULOS E. N., VERCAUTEREN J., CASTANAS E. J Pharmacol Exp Ther. 337, 24-32 (2011).

« Role of prostanoid receptors in the inhibitory effect of synthetic isoprostanes on potassium-induced [3H]D-aspartate release in isolated bovine retina. », KEGEY E., JAMIL J. M., HARRISON N., DURAND T., GALANO J.-M., GUY A., NJIE-MBYE Y. F., OHIA S. E., OPERE C. A. Faseb J. 25, 799.794 (2011).

« Oxidative stress in Rett syndrome : Natural history, genotype, and variants », LEONCINI S., DE FELICE C., SIGNORINI C., PECORELLI A., DURAND T., VALACCHI G., CICCOLI L., HAYEK J. Redox Report. 16, 145-153 (2011).

« Pharmacokinetic properties and metabolism of a new potent antimalarial N-alkylamidine compound, M64, and its corresponding bioprecursors », MARGOUT D., GATTACCECA F., MOARBESS G., WEIN S., TRAN VAN BA C., LE PAPE S., BERGER O., ESCALE R., VIAL H. J., BRESSOLLE F. M. Eur J Pharm Sci. 42, 81-90 (2011).

Publications 2004 /2011

Journaux à comité de lecture

  • « An Overview on Isoprostane Research : from Chemistry to Clinical Medicine. » LJ ROBERTS II, T. DURAND, Chem. Phys Lipids 128, 1-2 (2004).
  • « Total Syntheses of Iso- and Neuroprostanes : New Insight in Lipid Chemistry. » T. DURAND, A. GUY, O. HENRY, A. ROLAND, S. BERNAD, J-P. VIDAL, J-C ROSSI, Chem. Phys Lipids 128, 15-33 (2004).
  • « Total Syntheses of the Eight Diastereoisomers of the Syn-Anti-Syn Phytoprostanes F1 Types I an II. » S. EL FANGOUR, A. GUY, V. DESPRES, J-P. VIDAL, J-C ROSSI, T. DURAND, J. Org. Chem 69, 2498-2503 (2004).
  • « Synthesis of a photoactivatable potential inhibitor of the anandamide re-uptake » L. BALAS, M. HELLAL, J-C. ROSSI, T. DURAND, Nat Product Res. 19, 419-423 (2005).
  • « Different pharmacological profile of two close related ester endocannabionoid analogs » M. BOBROV, N. GRETSKAYA, O. PAYET, V. BEZUGLOV, T. DURAND, L. MAURIN, F. TOUREL, O. ADJALI, M. RINALDI-CARMONA, A. MULLER, Life Sciences 2005, 77, 1425-1440
  • « B1-phytoprostanes trigger plant defense and detoxification responses. » C. LOEFFLER, S. BERGER, A. GUY, T. DURAND, G. BRINGMANN, U VON RAD, J. DURNER, M.J. MUELLER, Plant Physiol. 137, 328-340 (2005).
  • « A Flexible Synthesis of the Phytoprostanes B1 Types I an II », S. EL FANGOUR, A. GUY, J-P. VIDAL, J-C ROSSI, T. DURAND, J. Org. Chem 70, 989-997 (2005).
  • « Isoprostanes 15-F2t-IsoP and 5-F2t-IsoP are not triggers of myocardial preconditioning. » C. ARNAUD, J-L. CRACOWSKI, A. HAKIM, T. DURAND, A. GUY, D. GODIN-RIBUOT, G. BESSARD, C. RIBUOT, Clin. Ex. Pharmacol. P. 32, 350-354 (2005).
  • « Enzymatic kinetic resolution of a functionalized 4-hydroxy-cyclopentenone : Synthesis of the key intermediates in the total synthesis of Isoprostanes. » E. PINOT, A. GUY, A-L. GUYON, J-C. ROSSI, T. DURAND, Tetrahedron Asymmetry. 16, 1893-1895(2005).
  • « Les Isoprostanes, Biomarqueurs de Peroxydation Lipidique chez l’Homme : Partie 1 : Nomenclature et Synthèse », T. DURAND, J-L. CRACOWSKI, O. BERDEAUX, Pathol. Biol. 53, 349-355 (2005).
  • « Les Isoprostanes, Biomarqueurs de Peroxydation Lipidique chez l’Homme : Partie 2 : Méthodes de Quantification », O. BERDEAUX, O. SCRUEL, T. DURAND, J-L. CRACOWSKI, Pathol. Biol. 53, 356-363, (2005).
  • « Les Isoprostanes, Biomarqueurs de Peroxydation Lipidique chez l’Homme : Partie 3 : Biomarqueurs et Médiateurs en Physiologie et Pathologie Vasculaire. » J-L. CRACOWSKI, O. BERDEAUX, T. DURAND, Pathol. Biol.53, 364-368 (2005).
  • « Synthesis of a potential photoactivatable anandamide analog », L. Balas, M. G. Cascio, V. Di Marzo and T. Durand, Bioorg Med Chem Lett 2006, 16, 3765-3768.
  • « F2-Isoprostanes : Review of Analytical Methods », O. Berdeaux, O. Scruel, J.-L. Cracowski and T. Durand, Current Pharmaceutical Analysis 2006, 2, 69-78.
  • « Cardiovascular pharmacology and physiology of the isoprostanes », J. L. Cracowski and T. Durand, Fundam Clin Pharmacol 2006, 20, 417-427.
  • « Asymmetric conformational changes in a GPCR dimer controlled by G-proteins », M. Damian, A. Martin, D. Mesnier, J. P. Pin and J. L. Baneres, Embo J 2006, 25, 5693-5702.

« Impact of diabetic polyneuropathy and cardiovascular autonomic neuropathy on the excretion of urinary 8-epi-PGF2alpha and its metabolites (2, 3-dinor and 2, 3-dinor-5, 6-dihydro) », J. Nourooz-Zadeh, C. G. Sohr, T. Durand and D. Ziegler, Free Radic Res 2006, 40, 723-729.

« Development of the first potential covalent inhibitors of anandamide cellular uptake », A. Schiano Moriello, L. Balas, A. Ligresti, M. G. Cascio, T. Durand, E. Morera, G. Ortar and V. Di Marzo, J Med Chem 2006, 49, 2320-2332.

« Potent antimalarial activity of 2-aminopyridinium salts, amidines, and guanidines », M. Calas, M. Ouattara, G. Piquet, Z. Ziora, Y. Bordat, M. L. Ancelin, R. Escale and H. Vial, J Med Chem 2007, 50, 6307-6315.

« Ibogaine and noribogaine : structural analysis and stability studies. Use of LC-MS to determine alkaloid contents of the root bark of Tabernanthe iboga », V. Kontrimaviciute, O. Mathieu, L. Balas, R. Escale, J. P. Blayac and F. M. M. Bressolle, Journal of Liquid Chromatography & Related Technologies 2007, 30, 1077-1092.

« Pharmacological actions of isoprostane metabolites and phytoprostanes in human and bovine pulmonary smooth muscles », C. Liu, T. Tazzeo, A. Guy, T. Durand and L. J. Janssen, Prostaglandins Leukot Essent Fatty Acids 2007, 76, 57-64.

« Synthesis and antimalarial activity of new 1,12-bis(N,N’-acetamidinyl)dodecane derivatives », M. Ouattara, S. Wein, M. Calas, Y. Vo-Hoang, H. Vial and R. Escale, Bioorg. Med. Chem. Lett. 2007, 17, 593-596.

« Beyond prostaglandins - Chemistry and biology of cyclic oxygenated metabolites formed by free-radical pathways from polyunsaturated fatty acids », U. Jahn, J. M. Galano and T. Durand, Angewandte Chemie-International Edition 2008, 47, 5894-5955.

« Quantification of urinary F2-isoprostanes with 4(RS)-F4t-neuroprostane as an internal standard using gas chromatography-mass spectrometry Application to polytraumatized patients », E. Mas, F. Michel, A. Guy, V. Bultel, Y. Falquet, P. Chardon, J. C. Rossi, J. P. Cristol and T. Durand, J Chromatogr B Analyt Technol Biomed Life Sci 2008, 872, 133-140.

« Stereocontrolled Access to Isoprostanes via a Bicyclo[3.3.0]octene Framework », C. Oger, Y. Brinkmann, S. Bouazzaoui, T. Durand and J. M. Galano, Organic Letters 2008, 10, 5087-5090.

« Total Synthesis of the Four Enantiomerically Pure Diasteroisomers of the Phytoprostanes E(1)Type II and of the 15-E(2t)-Isoprostanes », E. Pinot, A. Guy, A. Fournial, L. Balas, J. C. Rossi and T. Durand, J Org Chem 2008, 73, 3063-3069.

« Total synthesis of 4-F3t-neuroprostane and its 4-epimer », A.-L. Auvinet, B. Eignerová, A. Guy, M. Kotora and T. Durand, Tetrahedron Lett. 2009, 50, 1498-1500.

« Total synthesis of photoactivatable or fluorescent anandamide probes : novel bioactive compounds with angiogenic activity », L. Balas, T. Durand, S. Saha, I. Johnson and S. Mukhopadhyay, J. Med. Chem. 2009, 52, 1005-1017.

« Flaxseed oil supplementation increases plasma f1-phytoprostanes in healthy men », A. E. Barden, K. D. Croft, T. Durand, A. Guy, M. J. Mueller and T. A. Mori, J Nutr 2009, 139, 1890-1895.

« N-substituted bis-C-alkyloxadiazolones as dual effectors : efficient intermediates to amidoximes or amidines and prodrug candidates of potent antimalarials », M. Degardin, S. Wein, T. Durand, R. Escale, H. Vial and Y. Vo-Hoang, Bioorg Med Chem Lett 2009, 19, 5233-5236.

« New Bioactive Oxylipins Formed by Non-Enzymatic Free-Radical-Catalyzed Pathways : the Phytoprostanes », T. Durand, V. Bultel-Poncé, A. Guy, S. Berger, M. J. Mueller and J. M. Galano, Lipids 2009, 44, 875-888.

« Measurement of urinary F(2)-isoprostanes by gas chromatographymass spectrometry is confounded by interfering substances », E. Mas, A. Barden, T. Durand, J. M. Galano, K. D. Croft and T. A. Mori, Free Radic Res 2009.

« Design and synthesis of amidoxime derivatives for orally potent C-alkylamidine-based antimalarial agents », M. Ouattara, S. Wein, S. Denoyelle, S. Ortial, T. Durand, R. Escale, H. Vial and Y. Vo-Hoang, Bioorg. Med. Chem. Lett. 2009, 19, 624-626.

« Reverse-benzamidine antimalarial agents : Design, synthesis, and biological evaluation », O. Berger, S. Wein, J. F. Duckert, M. Maynadier, S. E. Fangour, R. Escale, T. Durand, H. Vial and Y. Vo-Hoang, Bioorg Med Chem Lett 2010, 20, 5815-5817.

« Total Synthesis of 15-D-2t- and 15-epi-15-E-2t-Isoprostanes », Y. Brinkmann, C. Oger, A. Guy, T. Durand and J. M. Galano, J. Org. Chem. 2010, 75, 2411-2414.

« A cautionary note on the correct structure assignment of phytoprostanes and the emergence of a new prostane ring system », U. Jahn, J. M. Galano and T. Durand, Prostaglandins Leukotrienes and Essential Fatty Acids 2010, 82, 83-86.

« Measurement of urinary F-2-isoprostanes by gas chromatography-mass spectrometry is confounded by interfering substances », E. Mas, A. Barden, T. Durand, J. M. Galano, K. D. Croft and T. A. Mori, Free Radic. Res. 2010, 44, 191-198.

« The omega-3 fatty acids EPA and DHA decrease plasma F(2)-isoprostanes : Results from two placebo-controlled interventions », E. Mas, R. J. Woodman, V. Burke, I. B. Puddey, L. J. Beilin, T. Durand and T. A. Mori, Free Radic Res 2010, 44, 983-990.

« The Handy Use of Brown’s P2-Ni Catalyst for a Skipped Diyne Deuteration : Application to the Synthesis of a D4 Labeled F(4t)-Neuroprostane », C. Oger, V. Bultel-Ponce, A. Guy, L. Balas, J. C. Rossi, T. Durand and J. M. Galano, Chemistry, a european journal 2010, 16, 13976-13980.

« New Insight in Lipase-Catalyzed Regioselective Monoacetylation of Unsymmetrical 1,5-Primary Diols », C. Oger, Z. Marton, Y. Brinkmann, V. Bultel-Poncé, T. Durand, M. Graber and J. M. Galano, J. Org. Chem. 2010, 75, 1892-1897.

« Synthesis and Evaluation of Hybrid Bis-cationic Salts as Antimalarial Drugs », S. Ortial, S. Denoyelle, S. Wein, O. Berger, T. Durand, R. Escale, A. Pellet, H. Vial and Y. Vo-Hoang, Chemmedchem 2010, 5, 52-55.

« Rapid access to structured triacylglycerols acylated with n-3 polyunsaturated fatty acids for nutritional applications », E. Vaique, A. Guy, L. Couedelo, I. Gosse, T. Durand, M. Cansell and S. Pinet, Tetrahedron 2010, 66, 8872-8879.

« Isoprostanes and phytoprostanes : Bioactive lipids », T. Durand, V. Bultel-Ponce, A. Guy, S. El Fangour, J. C. Rossi and J. M. Galano, Biochimie 2011, 93, 52-60.

« Symmetrical choline-derived dications display strong anti-kinetoplastid activity », H. M. Ibrahim, M. I. Al-Salabi, N. El Sabbagh, N. B. Quashie, A. A. Alkhaldi, R. Escale, T. K. Smith, H. J. Vial and H. P. de Koning, J Antimicrob Chemother 2011, 66, 111-125.

« Pharmacokinetic properties and metabolism of a new potent antimalarial N-alkylamidine compound, M64, and its corresponding bioprecursors », D. Margout, F. Gattacceca, G. Moarbess, S. Wein, C. Tran van Ba, S. Le Pape, O. Berger, R. Escale, H. J. Vial and F. M. Bressolle, Eur J Pharm Sci 2011, 42, 81-90.

Actes de colloques (avec comité de lecture)

1- « General Review on the Synthesis of Isoprostanes and Analogs », T. DURAND, A. GUY, J-P. VIDAL, J-C. ROSSI, Prostaglandins Leukot Essent Fatty Acids 71, 33-35 (2004)

2- « Total Synthesis of Iso-and Neuroprostanes : biomarkers of lipid peroxidation. », A. GUY, A. FOURNIAL, S. BERNAD, O. HENRY, J-P. VIDAL, J-C. ROSSI, T. DURAND, Prostaglandins Leukot Essent Fatty Acids 71, 49-50 (2004).

3- « Total Synthesis of Phytoprostanes F1 type I and II », S. EL FANGOUR, A. GUY, V. DESPRES, J-P. VIDAL, J-C. ROSSI, T. DURAND, Prostaglandins Leukot Essent Fatty Acids 71, 50-51 (2004).

4- « Total Synthesis of Phytoprostanes B1 », S. EL FANGOUR, A. GUY, J-P. VIDAL, J-C. ROSSI, T. DURAND, Prostaglandins Leukot Essent Fatty Acids 71, 51-52 (2004).

Articles généraux, revues

Beyond prostaglandins—chemistry and biology of cyclic oxygenated metabolites formed by free-radical pathways from polyunsaturated fatty acids, U. Jahn, J. M. Galano, T. Durand, Angew. Chem. Int. Ed. 47 (2008) 5894-955.

« Radical Cyclization of highly functionalized 1-susbtituted-2,4-dihydroxylated-hex-5-enyl radicals : Useful tools for the synthesis of Iso-and Neuroprostanes. » T. DURAND, A. GUY, O. HENRY, A. ROLAND, S. BERNAD, J-P. VIDAL AND J-C ROSSI, Recent Res. Devel. Organic Chem., 6 (Part II), 521-530 (2002).


H.J. VIAL, M. CALAS, R. ESCALE, V. VIDAL-SAILHAN, F. BRESSOLLE, M.L. ANCELIN, Composés à activités antiparasitaires et médicaments les contenant. Applied by CNRS, N° 0209156, July, 18, 2002, PCT/FR03/02283, July, 18, 2003, WO 2004/009068. Patent and know how in the field of human health have been licenced to Sanofi Synthelabo, Dec 2002.

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